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Ces2a Gene Detail
Summary
  • Symbol
    Ces2a
  • Name
    carboxylesterase 2A
  • Synonyms
    9130231C15Rik, Ces6
  • Feature Type
    protein coding gene
  • IDs
    MGI:2142491
    NCBI Gene: 102022
  • Gene Overview
    MyGene.info: CES2
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:104734003-104741634 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 53.04 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    59 from dbSNP Build 142
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2142491
protein coding gene Chr8:104734003-104741634 (+)
129S1/SvImJ MGP_129S1SvImJ_G0034018
protein coding gene Chr8:106900017-106909506 (+)
A/J MGP_AJ_G0033999
protein coding gene Chr8:102662086-102669925 (+)
AKR/J MGP_AKRJ_G0033925
protein coding gene Chr8:105627592-105634700 (+)
BALB/cJ MGP_BALBcJ_G0033992
protein coding gene Chr8:102864078-102872259 (+)
C3H/HeJ MGP_C3HHeJ_G0033704
protein coding gene Chr8:106342138-106352535 (+)
C57BL/6NJ MGP_C57BL6NJ_G0034512
protein coding gene Chr8:110819033-110825927 (+)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0033031
protein coding gene Chr8:105885975-105901393 (+)
CBA/J MGP_CBAJ_G0033678
protein coding gene Chr8:114505436-114506608 (+)
DBA/2J MGP_DBA2J_G0033832
protein coding gene Chr8:102001834-102009473 (+)
FVB/NJ MGP_FVBNJ_G0033779
protein coding gene Chr8:100940895-100951181 (+)
LP/J MGP_LPJ_G0033923
protein coding gene Chr8:107080328-107096859 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033821
protein coding gene Chr8:117666976-117677187 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0034530
protein coding gene Chr8:105570009-105581622 (+)
PWK/PhJ MGP_PWKPhJ_G0032733
protein coding gene Chr8:101411802-101433626 (+)
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0033146
protein coding gene Chr8:106268685-106281931 (+)



Homology
more
  • Human Ortholog
    CES2, carboxylesterase 2
  • Vertebrate Orthologs
    2
  • Human Ortholog
    CES2, carboxylesterase 2
    Orthology source: HGNC
  • Synonyms
    CE-2, CES2A1, iCE, PCE-2
  • Links
    NCBI Gene ID: 8824
    neXtProt AC: NX_O00748
    UniProt: O00748

  • Chr Location
    16q22.1; chr16:66934444-66945096 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 102022 NCBI Gene Model | MGI Sequence Detail 7632 C57BL/6J ±  kb
transcript NM_133960 RefSeq | MGI Sequence Detail 1964 C57BL/6  
polypeptide Q8QZR3 UniProt | EBI | MGI Sequence Detail 558 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 63
    cDNA 63

    Microarray probesets 3
References
more
  • Summaries
    All 27
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 3
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:272586 Suzuki T, et al., Postnatal liver functional maturation requires Cnot complex-mediated decay of mRNAs encoding cell cycle and immature liver genes. Development. 2019 Feb 15;146(4)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory