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Ido2
Gene Detail
 Symbol
Name
ID
Ido2
indoleamine 2,3-dioxygenase 2
MGI:2142489
Synonyms C230043N17Rik, Ido2, Indol1, MGC:31194
Feature Type protein coding gene
Genetic Map
Chromosome 8
12.58 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr8:24531894-24576333 bp, - strand
From VEGA annotation of GRCm38

  44440 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:48830  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: indoleamine 2,3-dioxygenase
Gene Tree: Ido2

Human
homologs
Human Homolog IDO2, indoleamine 2,3-dioxygenase 2
NCBI Gene ID 169355
neXtProt AC  NX_Q6ZQW0
Human Synonyms  INDOL1
Human Chr (Location)  8p11.21; chr8:39934955-40016391 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Ido2 interacts with 228 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (58 annotations)
Process oxidation-reduction process, tryptophan catabolic process to kynurenine
Component cytoplasm
Function 1,1-dichloro-2-(dihydroxy-4-chlorophenyl)-(4-chlorophenyl)ethene 1,2-dioxygenase activity, 1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene extradiol dioxygenase activity, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (94)    Tissues (94)   
Theiler Stages: 22
Assay TypeResults
RNA in situ 94
cDNA source data(4)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(4) cDNA(4)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000029868 (Evidence)
Ensembl Gene ModelENSMUSG00000031549 (Evidence)
Entrez Gene209176 (Evidence)
DFCITC1588804, TC1622894
DoTSDT.101721109, DT.40183944
NIA Mouse Gene IndexU029651
EC1.13.11.-
Consensus CDS ProjectCCDS40298.2
International Mouse Knockout Project StatusIdo2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000029868 VEGA Gene Model | MGI Sequence Detail 44440 C57BL/6J ±  kb
transcript OTTMUST00000074117 VEGA | MGI Sequence Detail 2452 Not Applicable 
polypeptide OTTMUSP00000038470 VEGA | MGI Sequence Detail 405 Not Applicable 

For the selected sequences
All sequences(38) RefSeq(8) UniProt(3)
Polymorphisms SNPs within 2kb(117 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000898 Indoleamine 2,3-dioxygenase
Protein Ontology PR:000009031 indoleamine 2,3-dioxygenase 2
References (Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:203966 Mazarei G, et al., Age-dependent alterations of the kynurenine pathway in the YAC128 mouse model of Huntington disease. J Neurochem. 2013 Dec;127(6):852-67
All references(34)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory