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Ido2
Gene Detail
Symbol

Name
ID
Ido2
indoleamine 2,3-dioxygenase 2
MGI:2142489
Synonyms
C230043N17Rik, Ido2, Indol1, MGC:31194
Feature Type
protein coding gene
Genetic Map
Chromosome 8
12.58 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr8:24531894-24576333 bp, - strand
From VEGA annotation of GRCm38

  44440 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:48830  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: IDO2
Protein SuperFamily: indoleamine 2,3-dioxygenase
Gene Tree: Ido2

Human
homologs
IDO2, indoleamine 2,3-dioxygenase 2
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 169355
neXtProt AC: NX_Q6ZQW0

Human Synonyms: INDOL1

Human Chr (Location): 8p11.21; chr8:39934955-40016391 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit impaired T cell function and decreased susceptibility to type IV hypersensitivity reaction.
 
Interactions
Ido2 interacts with 228 markers (Mir1b, Mir7-1, Mir7-2, ...)
Expression
Literature Summary: (2 records)
Data Summary: Results (94)    Tissues (94)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
cDNA source data(4)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(4) cDNA(4)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000029868 (Evidence)
Ensembl Gene Model ENSMUSG00000031549 (Evidence)
Entrez Gene 209176 (Evidence)
DFCI TC1622894, TC1588804
DoTS DT.40183944, DT.101721109
NIA Mouse Gene Index U029651
EC 1.13.11.-
Consensus CDS Project CCDS40298.2
International Mouse Phenotyping Consortium Status Ido2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000029868 VEGA Gene Model | MGI Sequence Detail 44440 C57BL/6J ±  kb
transcript OTTMUST00000074117 VEGA | MGI Sequence Detail 2452 Not Applicable 
polypeptide OTTMUSP00000038470 VEGA | MGI Sequence Detail 405 Not Applicable 

For the selected sequences
All sequences(40) RefSeq(12) UniProt(3)
Polymorphisms
SNPs within 2kb(117 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000898 Indoleamine 2,3-dioxygenase
Protein Ontology PR:000009031 indoleamine 2,3-dioxygenase 2
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:213564 Bessede A, et al., Aryl hydrocarbon receptor control of a disease tolerance defence pathway. Nature. 2014 Jul 10;511(7508):184-90
All references(36)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory