Usb1
Gene Detail

Symbol Name ID

Usb1 U6 snRNA biogenesis 1 MGI:2142454

Synonyms

AA960436

Feature Type

protein coding gene

Genetic Map

Chromosome 8

47.12 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr8:95332292-95347507 bp, + strand From VEGA annotation of GRCm38   15216 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:11611  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Usb1

Human homologs

Human Homolog		USB1, U6 snRNA biogenesis 1
NCBI Gene ID		79650
neXtProt AC		NX_Q9BQ65
Human Synonyms		C16orf57, hUsb1, HVSL1, Mpn1, PN
Human Chr (Location)		16q21; chr16:58035277-58055527 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human USB1

Alleles and phenotypes

All alleles(5) : Targeted(3) Gene trapped(2)

Gene Ontology (GO) classifications

All GO classifications: (8 annotations)

Process	mRNA processing, RNA splicing, ...
Component	nucleus
Function	3'-5'-exoribonuclease activity, hydrolase activity, ...

This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase

Expression

cDNA source data(47)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(47) cDNA(47)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000031300 (Evidence)
Ensembl Gene Model	ENSMUSG00000031792 (Evidence)
Entrez Gene	101985 (Evidence)
UniGene	29069
DFCI	TC1578171, TC1702879
DoTS	DT.110845729, DT.530655
NIA Mouse Gene Index	U009685
EC	3.1.4.-
Consensus CDS Project	CCDS22560.1
International Mouse Knockout Project Status	Usb1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000031300	VEGA Gene Model | MGI Sequence Detail	15216	C57BL/6J
transcript	OTTMUST00000077545	VEGA | MGI Sequence Detail	1750	Not Applicable
polypeptide	OTTMUSP00000041036	VEGA | MGI Sequence Detail	267	Not Applicable

All sequences(37) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(56 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR027521	Putative U6 snRNA phosphodiesterase

References

(Earliest) J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(30)