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Usb1
Gene Detail
 Symbol
Name
ID
Usb1
U6 snRNA biogenesis 1
MGI:2142454
Synonyms AA960436
Feature Type protein coding gene
Genetic Map
Chromosome 8
47.12 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr8:95332292-95347507 bp, + strand
From VEGA annotation of GRCm38

  15216 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:11611  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Usb1

Human
homologs
Human Homolog USB1, U6 snRNA biogenesis 1
NCBI Gene ID 79650
neXtProt AC  NX_Q9BQ65
Human Synonyms  C16orf57, hUsb1, HVSL1, Mpn1, PN
Human Chr (Location)  16q21; chr16:57999605-58021623 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human USB1
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(2) Targeted(3)
Incidental mutations (data from APF )
Interactions
Usb1 interacts with 172 markers (Mir10a, Mir10b, Mir15a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (20 annotations)
Process mRNA processing, RNA phosphodiester bond hydrolysis, exonucleolytic, ...
Component nucleus
Function 3',5'-cyclic-AMP phosphodiesterase activity, 3'-5'-exoribonuclease activity, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
cDNA source data(49)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(49) cDNA(49)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000031300 (Evidence)
Ensembl Gene ModelENSMUSG00000031792 (Evidence)
Entrez Gene101985 (Evidence)
UniGene29069
DFCITC1578171, TC1702879
DoTSDT.110845729, DT.530655
NIA Mouse Gene IndexU009685
EC3.1.4.-
Consensus CDS ProjectCCDS22560.1
International Mouse Knockout Project StatusUsb1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031300 VEGA Gene Model | MGI Sequence Detail 15216 C57BL/6J ±  kb
transcript OTTMUST00000077545 VEGA | MGI Sequence Detail 1750 Not Applicable 
polypeptide OTTMUSP00000041036 VEGA | MGI Sequence Detail 267 Not Applicable 

For the selected sequences
All sequences(39) RefSeq(4) UniProt(2)
Polymorphisms SNPs within 2kb(106 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027521 Putative U6 snRNA phosphodiesterase
InterPro IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase
References (Earliest) J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(31)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/16/2014
MGI 5.19
The Jackson Laboratory