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Misfadt Gene Detail
Summary
  • Symbol
    Misfadt
  • Name
    mitochondrial sheath formation associated divergent transcript
  • Synonyms
    C86187, Sirena1
  • Feature Type
    lncRNA gene
  • IDs
    MGI:2142361
    NCBI Gene: 97402
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:46617458-46625659 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 30.65 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    407 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2142361
 lncRNA gene Chr7:46617454-46625659 (-)
129S1/SvImJ ENSMUSG00200032706
 lncRNA gene Chr7:34235231-34243436 (-)
A/J ENSMUSG00195049269
 lncRNA gene Chr7:38251608-38259813 (-)
AKR/J ENSMUSG00220009118
 lncRNA gene Chr7:32546972-32555178 (-)
BALB/cJ ENSMUSG00180043862
 lncRNA gene Chr7:35126993-35135199 (-)
C3H/HeJ ENSMUSG00175040509
 lncRNA gene Chr7:35671143-35679348 (-)
C57BL/6NJ ENSMUSG00215046247
 lncRNA gene Chr7:34910624-34918830 (-)
CAROLI/EiJ no annotation
CAST/EiJ ENSTCUG00005048090
 lncRNA gene Chr7:38655762-38663477 (-)
CBA/J ENSMUSG00210050394
 lncRNA gene Chr7:36021526-36029732 (-)
DBA/2J ENSMUSG00185050358
 lncRNA gene Chr7:39917984-39926189 (-)
FVB/NJ ENSMUSG00205048111
 lncRNA gene Chr7:35566133-35574339 (-)
JF1/MsJ ENSUMUG00000055289
 lncRNA gene Chr7:44403332-44411070 (-)
LP/J ENSMUSG00230051841
 lncRNA gene Chr7:45342634-45350853 (-)
NOD/ShiLtJ ENSMUSG00190050408
 lncRNA gene Chr7:35893763-35901968 (-)
NZO/HlLtJ ENSMUSG00225018718
 lncRNA gene Chr7:43545512-43553717 (-)
PWK/PhJ ENSLUMG00010049503
 lncRNA gene Chr7:34864918-34872630 (-)
SPRET/EiJ ENSMSPG00010045271
 lncRNA gene Chr7:34647447-34655397 (-)
WSB/EiJ ENSIUOG00005031284
 lncRNA gene Chr7:36448478-36456692 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    1 phenotype reference
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit oocytes with altered distribution of mitochondria in the perinuclear space but normal fertility.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    60
Sequences &
Gene Models
less
  • All Sequences
    35
  • RefSeq
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 97402 NCBI Gene Model | MGI Sequence Detail 8202 C57BL/6J ±  kb
transcript NR_015609 RefSeq | MGI Sequence Detail 2057 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 60
    cDNA 60

    Microarray probesets 1
Other
Accession IDs
less
MGI:7567960
References
more
  • Summaries
    All 12
    Phenotypes 1
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:291605 Ganesh S, et al., The most abundant maternal lncRNA Sirena1 acts post-transcriptionally and impacts mitochondrial distribution. Nucleic Acids Res. 2020 Apr 6;48(6):3211-3227
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory