About   Help   FAQ
Mtmr10 Gene Detail
Summary
  • Symbol
    Mtmr10
  • Name
    myotubularin related protein 10
  • Feature Type
    protein coding gene
  • IDs
    MGI:2142292
    NCBI Gene: 233315
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:63937443-63990556 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 34.63 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1553 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2142292
 protein coding gene Chr7:63937401-63990556 (+)
129S1/SvImJ MGP_129S1SvImJ_G0032335
 protein coding gene Chr7:65423689-65478805 (+)
A/J MGP_AJ_G0032314
 protein coding gene Chr7:64157703-64211356 (+)
AKR/J MGP_AKRJ_G0032250
 protein coding gene Chr7:65512793-65567271 (+)
BALB/cJ MGP_BALBcJ_G0032326
 protein coding gene Chr7:63898003-63950904 (+)
C3H/HeJ MGP_C3HHeJ_G0032039
 protein coding gene Chr7:66159991-66217421 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032819
 protein coding gene Chr7:68228167-68301855 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029826
 protein coding gene Chr7:67103467-67156908 (+)
CAST/EiJ MGP_CASTEiJ_G0031368
 protein coding gene Chr7:56856851-56911373 (+)
CBA/J MGP_CBAJ_G0032005
 protein coding gene Chr7:70452682-70505755 (+)
DBA/2J MGP_DBA2J_G0032161
 protein coding gene Chr7:62909567-62962936 (+)
FVB/NJ MGP_FVBNJ_G0032115
 protein coding gene Chr7:63009038-63061954 (+)
LP/J MGP_LPJ_G0032241
 protein coding gene Chr7:66656527-66716272 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0032152
 protein coding gene Chr7:70726739-70780807 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032836
 protein coding gene Chr7:64794960-64850285 (+)
PWK/PhJ MGP_PWKPhJ_G0031088
 protein coding gene Chr7:55918712-55972192 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030929
 protein coding gene Chr7:51932436-51986889 (+)
WSB/EiJ MGP_WSBEiJ_G0031486
 protein coding gene Chr7:65178696-65233933 (+)



Homology
more
  • Human Ortholog
    MTMR10, myotubularin related protein 10
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MTMR10, myotubularin related protein 10
  • Links
    NCBI Gene ID: 54893
    UniProt: Q9NXD2

  • Chr Location
    15q13.3; chr15:30918716-30991628 (-)  GRCh38
Human Diseases
less
  • References
    2 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 2 alleles in 2 genetic backgrounds
    1 phenotype from multigenic genotypes
    25 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit normal preweaning survival.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    2
Molecular Function

Biological Process

Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    796
  • Tissues
    12
  • cDNA Data
    83
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 233315 NCBI Gene Model | MGI Sequence Detail 53114 C57BL/6J ±  kb
transcript NM_172742 RefSeq | MGI Sequence Detail 5182 C57BL/6  
polypeptide Q7TPM9 UniProt | EBI | MGI Sequence Detail 771 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000010732 myotubularin-related protein 10
    (term hierarchy)
  • InterPro Domains
    IPR036004 MTMR10, PH-GRAM domain
    IPR030564 Myotubularin family
    IPR010569 Myotubularin-like, phosphatase domain
    IPR022587 Myotubularin-related 12-like C-terminal domain
    IPR030573 Myotubularin-related protein 10, protein tyrosine phosphatase domain
    IPR011993 PH-like domain superfamily
    IPR029021 Protein-tyrosine phosphatase-like
  • GlyGen
    Q7TPM9 1 site, 1 N-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 83
    cDNA 83

    Microarray probesets 5
Other
Accession IDs
less
MGI:2142333
References
more
  • Summaries
    All 50
    Developmental Gene Expression 2
    Diseases 2
    Gene Ontology 2
    Phenotypes 25
  • Earliest
    J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
  • Latest
    J:348102 Unda BK, et al., Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome. Mol Psychiatry. 2023 Apr;28(4):1747-1769
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory