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Leng8 Gene Detail
Summary
  • Symbol
    Leng8
  • Name
    leukocyte receptor cluster (LRC) member 8
  • Feature Type
    protein coding gene
  • IDs
    MGI:2142195
    NCBI Gene: 232798
  • Alliance
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:4137053-4148177 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 2.39 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    64 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2142195
protein coding gene Chr7:4137039-4148177 (+)
129S1/SvImJ MGP_129S1SvImJ_G0031538
protein coding gene Chr7:1060701-1071853 (+)
A/J MGP_AJ_G0031512
protein coding gene Chr7:1039362-1050506 (+)
AKR/J MGP_AKRJ_G0031440
protein coding gene Chr7:1096736-1107886 (+)
BALB/cJ MGP_BALBcJ_G0031520
protein coding gene Chr7:1112892-1124035 (+)
C3H/HeJ MGP_C3HHeJ_G0031241
protein coding gene Chr7:1093543-1104708 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031981
protein coding gene Chr7:1092273-1103468 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029105
protein coding gene Chr7:836290-847381 (+)
CAST/EiJ MGP_CASTEiJ_G0030605
protein coding gene Chr7:1036006-1047142 (+)
CBA/J MGP_CBAJ_G0031199
protein coding gene Chr7:1287049-1298193 (+)
DBA/2J MGP_DBA2J_G0031358
protein coding gene Chr7:1020284-1031416 (+)
FVB/NJ MGP_FVBNJ_G0031310
protein coding gene Chr7:1001957-1013101 (+)
LP/J MGP_LPJ_G0031443
protein coding gene Chr7:1152979-1164154 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031349
protein coding gene Chr7:1165345-1176489 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032011
protein coding gene Chr7:1034177-1045315 (+)
PWK/PhJ MGP_PWKPhJ_G0030333
protein coding gene Chr7:1223045-1234209 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030158
protein coding gene Chr7:1163826-1174974 (+)
WSB/EiJ MGP_WSBEiJ_G0030700
protein coding gene Chr7:1063344-1074474 (+)



Homology
more
  • Human Ortholog
    LENG8, leukocyte receptor cluster member 8
  • Vertebrate Orthologs
    10
  • Human Ortholog
    LENG8, leukocyte receptor cluster member 8
    Orthology source: HomoloGene, HGNC
  • Synonyms
    pp13842
  • Links
    NCBI Gene ID: 114823
    neXtProt AC: NX_Q96PV6
    UniProt: Q96PV6

  • Chr Location
    19q13.42; chr19:54448719-54462046 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 232798 NCBI Gene Model | MGI Sequence Detail 11125 C57BL/6J ±  kb
transcript NM_172736 RefSeq | MGI Sequence Detail 5094 C57BL/6  
polypeptide Q8CBY3 UniProt | EBI | MGI Sequence Detail 785 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 86
    cDNA 86

    Microarray probesets 5
References
more
  • Summaries
    All 27
    Developmental Gene Expression 4
    Gene Ontology 1
    Phenotypes 3
  • Earliest
    J:93300 Blackshaw S, et al., Genomic analysis of mouse retinal development. PLoS Biol. 2004 Oct;2(9):E247
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory