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Spred3 Gene Detail
Summary
  • Symbol
    Spred3
  • Name
    sprouty-related, EVH1 domain containing 3
  • Synonyms
    D130060H24Rik, Spred-3
  • Feature Type
    protein coding gene
  • IDs
    MGI:2142186
    NCBI Gene: 101809
  • Gene Overview
    MyGene.info: SPRED3
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:29158829-29170411 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 16.94 cM, cytoband A3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    46 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2142186
protein coding gene Chr7:29157267-29170411 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031973
protein coding gene Chr7:28066224-28077230 (-)
A/J MGP_AJ_G0031951
protein coding gene Chr7:27325926-27334282 (-)
AKR/J MGP_AKRJ_G0031883
protein coding gene Chr7:28024554-28035552 (-)
BALB/cJ MGP_BALBcJ_G0031958
protein coding gene Chr7:27489752-27502177 (-)
C3H/HeJ MGP_C3HHeJ_G0031677
protein coding gene Chr7:28430383-28441385 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032422
protein coding gene Chr7:28954323-28964294 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029474
protein coding gene Chr7:28386262-28394785 (-)
CAST/EiJ MGP_CASTEiJ_G0031012
protein coding gene Chr7:21731088-21742116 (-)
CBA/J MGP_CBAJ_G0031643
protein coding gene Chr7:30306673-30314975 (-)
DBA/2J MGP_DBA2J_G0031795
protein coding gene Chr7:27062948-27073937 (-)
FVB/NJ MGP_FVBNJ_G0031752
protein coding gene Chr7:27154998-27171157 (-)
LP/J MGP_LPJ_G0031875
protein coding gene Chr7:28360174-28368492 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031788
protein coding gene Chr7:29685584-29693898 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032452
protein coding gene Chr7:27516548-27529141 (-)
PWK/PhJ MGP_PWKPhJ_G0030737
protein coding gene Chr7:22111306-22119678 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030570
protein coding gene Chr7:18542997-18551234 (-)
WSB/EiJ MGP_WSBEiJ_G0031121
protein coding gene Chr7:27889123-27897331 (-)



Homology
more
  • Human Ortholog
    SPRED3, sprouty related EVH1 domain containing 3
  • Vertebrate Orthologs
    7
  • Human Ortholog
    SPRED3, sprouty related EVH1 domain containing 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    Eve-3, spred-3
  • Links
    NCBI Gene ID: 399473
    neXtProt AC: NX_Q2MJR0
    UniProt: Q2MJR0

  • Chr Location
    19q13.2; chr19:38390061-38399884 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000037239 Ensembl Gene Model | MGI Sequence Detail 11583 C57BL/6J ±  kb
transcript ENSMUST00000048923 Ensembl | MGI Sequence Detail 4056 Not Applicable  
polypeptide ENSMUSP00000046216 Ensembl | MGI Sequence Detail 408 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 14
    cDNA 13
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 28
    Developmental Gene Expression 3
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:259186 Heng X, et al., Analogous mechanism regulating formation of neocortical basal radial glia and cerebellar Bergmann glia. Elife. 2017 May 10;6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory