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Spred3
Gene Detail
Symbol

Name
ID
Spred3
sprouty-related, EVH1 domain containing 3
MGI:2142186
Synonyms
D130060H24Rik, Spred-3
Feature Type
protein coding gene
Genetic Map
Chromosome 7
16.94 cM, cytoband A3
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr7:29158829-29169841 bp, - strand
From VEGA annotation of GRCm38

  11013 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:28061  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Protein SuperFamily: sprouty-related protein Spred
Gene Tree: Spred3

Human
homologs
Human Homolog SPRED3, sprouty-related, EVH1 domain containing 3
NCBI Gene ID 399473
neXtProt AC  NX_Q2MJR0
Human Synonyms  Eve-3, spred-3
Human Chr (Location)  19q13; chr19:38389979-38399884 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Gene trapped(2) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Spred3 interacts with 234 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process inactivation of MAPK activity, multicellular organismal development, ...
Component membrane, plasma membrane
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (145)    Tissues (17)    Images (22)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 143
RT-PCR 2
cDNA source data(12)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(13) cDNA(12) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000023179 (Evidence)
Ensembl Gene ModelENSMUSG00000037239 (Evidence)
Entrez Gene101809 (Evidence)
UniGene377262
DFCITC1598713, TC1599121, TC1619202
DoTSDT.101138208, DT.91283382, DT.94184471
NIA Mouse Gene IndexU028345
Consensus CDS ProjectCCDS21065.1
International Mouse Knockout Project StatusSpred3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023179 VEGA Gene Model | MGI Sequence Detail 11013 C57BL/6J ±  kb
transcript OTTMUST00000056065 VEGA | MGI Sequence Detail 4056 Not Applicable 
polypeptide OTTMUSP00000026899 VEGA | MGI Sequence Detail 408 Not Applicable 

For the selected sequences
All sequences(40) RefSeq(14) UniProt(1)
Polymorphisms
SNPs within 2kb(46 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR023337 c-Kit-binding domain
InterPro IPR000697 EVH1
InterPro IPR011993 Pleckstrin homology-like domain
InterPro IPR007875 Sprouty
Protein Ontology PR:000015570 sprouty-related, EVH1 domain-containing protein 3
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(31)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory