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Alkbh6 Gene Detail
Summary
  • Symbol
    Alkbh6
  • Name
    alkB homolog 6
  • Synonyms
    Abh6
  • Feature Type
    protein coding gene
  • IDs
    MGI:2142037
    NCBI Gene: 233065
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:30308753-30314303 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 17.38 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    101 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2142037
protein coding gene Chr7:30308717-30314304 (+)
129S1/SvImJ MGP_129S1SvImJ_G0032012
protein coding gene Chr7:29293255-29298851 (+)
A/J MGP_AJ_G0031989
protein coding gene Chr7:28518320-28523929 (+)
AKR/J MGP_AKRJ_G0031922
protein coding gene Chr7:29249993-29255610 (+)
BALB/cJ MGP_BALBcJ_G0031996
protein coding gene Chr7:28693901-28699520 (+)
C3H/HeJ MGP_C3HHeJ_G0031715
protein coding gene Chr7:29692596-29698183 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032462
protein coding gene Chr7:30245582-30251169 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029512
protein coding gene Chr7:29554381-29560171 (+)
CAST/EiJ MGP_CASTEiJ_G0031049
protein coding gene Chr7:22945825-22951446 (+)
CBA/J MGP_CBAJ_G0031681
protein coding gene Chr7:31704551-31710138 (+)
DBA/2J MGP_DBA2J_G0031833
protein coding gene Chr7:28247838-28253453 (+)
FVB/NJ MGP_FVBNJ_G0031790
protein coding gene Chr7:28365695-28371274 (+)
LP/J MGP_LPJ_G0031914
protein coding gene Chr7:29614659-29620276 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031826
protein coding gene Chr7:30954718-30960305 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032490
protein coding gene Chr7:28748920-28754507 (+)
PWK/PhJ MGP_PWKPhJ_G0030775
protein coding gene Chr7:23282644-23288247 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030608
protein coding gene Chr7:19749214-19755706 (+)
WSB/EiJ MGP_WSBEiJ_G0031159
protein coding gene Chr7:29129744-29135363 (+)



Homology
more
  • Human Ortholog
    ALKBH6, alkB homolog 6
  • Vertebrate Orthologs
    6
  • Human Ortholog
    ALKBH6, alkB homolog 6
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ABH6
  • Links
    NCBI Gene ID: 84964
    neXtProt AC: NX_Q3KRA9
    UniProt: Q3KRA9

  • Chr Location
    19q13.12; chr19:36009116-36014243 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 233065 NCBI Gene Model | MGI Sequence Detail 5551 C57BL/6J ±  kb
    transcript NM_198027 RefSeq | MGI Sequence Detail 945 C57BL/6  
    polypeptide Q8K2U2 UniProt | EBI | MGI Sequence Detail 238 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      3 Sequences
    • Protein Ontology
      PR:000003953 alpha-ketoglutarate-dependent dioxygenase alkB homolog 6
    • EC
    • InterPro Domains
      IPR032862 Alpha-ketoglutarate-dependent dioxygenase alkB homologue 6
      IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like
      IPR037151 Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily
      IPR005123 Oxoglutarate/iron-dependent dioxygenase
    Molecular
    Reagents
    less
    • All nucleic 83
      cDNA 83

      Microarray probesets 3
    References
    more
    • Summaries
      All 29
      Gene Ontology 4
      Phenotypes 7
    • Earliest
      J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
    • Latest
      J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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    Funding Information
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    last database update
    03/24/2020
    MGI 6.15
    The Jackson Laboratory