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Pwwp2b Gene Detail
Summary
  • Symbol
    Pwwp2b
  • Name
    PWWP domain containing 2B
  • Synonyms
    D7Ertd517e, D930023J19Rik, Pwwp2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2142008
    NCBI Gene: 101631
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:139248482-139267256 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 84.39 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    188 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2142008
protein coding gene Chr7:139248482-139269903 (+)
129S1/SvImJ MGP_129S1SvImJ_G0033149
protein coding gene Chr7:144259645-144278416 (+)
A/J MGP_AJ_G0033131
protein coding gene Chr7:140184034-140202817 (+)
AKR/J MGP_AKRJ_G0033063
protein coding gene Chr7:143962456-143981305 (+)
BALB/cJ MGP_BALBcJ_G0033132
protein coding gene Chr7:139926245-139945001 (+)
C3H/HeJ MGP_C3HHeJ_G0032846
protein coding gene Chr7:143780980-143799750 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033643
protein coding gene Chr7:149581479-149601445 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030616
protein coding gene Chr7:141324443-141343316 (+)
CAST/EiJ MGP_CASTEiJ_G0032176
protein coding gene Chr7:136070137-136156145 (+)
CBA/J MGP_CBAJ_G0032819
protein coding gene Chr7:154633324-154652106 (+)
DBA/2J MGP_DBA2J_G0032971
protein coding gene Chr7:138143085-138161843 (+)
FVB/NJ MGP_FVBNJ_G0032924
protein coding gene Chr7:138027175-138045949 (+)
LP/J MGP_LPJ_G0033065
protein coding gene Chr7:145804152-145822909 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0032956
protein coding gene Chr7:155338497-155357277 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033663
protein coding gene Chr7:142966509-142985283 (+)
PWK/PhJ MGP_PWKPhJ_G0031882
protein coding gene Chr7:131314456-131393233 (+)
SPRET/EiJ MGP_SPRETEiJ_G0031727
protein coding gene Chr7:129798571-129817444 (+)
WSB/EiJ MGP_WSBEiJ_G0032287
protein coding gene Chr7:143880243-143900197 (+)



Homology
more
  • Human Ortholog
    PWWP2B, PWWP domain containing 2B
  • Vertebrate Orthologs
    8
  • Human Ortholog
    PWWP2B, PWWP domain containing 2B
    Orthology source: HomoloGene, HGNC
  • Synonyms
    bA432J24.1, pp8607, PWWP2
  • Links
    NCBI Gene ID: 170394
    neXtProt AC: NX_Q6NUJ5
    UniProt: Q6NUJ5

  • Chr Location
    10q26.3; chr10:132397196-132417863 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 101631 NCBI Gene Model | MGI Sequence Detail 18775 C57BL/6J ±  kb
transcript NM_001098636 RefSeq | MGI Sequence Detail 2640 C57BL/6  
polypeptide NP_001092106 RefSeq | MGI Sequence Detail 600 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR000313 PWWP domain
Molecular
Reagents
less
  • All nucleic 30
    cDNA 29
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:1261860
References
more
  • Summaries
    All 27
    Gene Ontology 1
    Phenotypes 2
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
12/03/2019
MGI 6.14
The Jackson Laboratory