Mice homozygous for a targeted allele exhibit increased susceptibility to DSS-induced colitis, decreased circulating and colonic IL18 levels, colonic crypt hyperplasia, enlarged Peyer's patches, increased IgG2c and IgA serum levels, increased leukocytes, and expanded gut bacterial phylotypes.
|VEGA Gene Model||OTTMUSG00000044619 (Evidence)|
|Ensembl Gene Model||ENSMUSG00000038745 (Evidence)|
|Entrez Gene||101613 (Evidence)|
|DoTS||DT.94193894, DT.40173544, DT.101365136, DT.101365135|
|NIA Mouse Gene Index||U008940|
|Consensus CDS Project||CCDS40178.2|
|International Mouse Knockout Project Status||Nlrp6|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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