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Grwd1 Gene Detail
Summary
  • Symbol
    Grwd1
  • Name
    glutamate-rich WD repeat containing 1
  • Synonyms
    WDR28
  • Feature Type
    protein coding gene
  • IDs
    MGI:2141989
    NCBI Gene: 101612
  • Gene Overview
    MyGene.info: GRWD1
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:45825223-45830944 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 29.53 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    59 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2141989
protein coding gene Chr7:45825223-45830994 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032250
protein coding gene Chr7:46147118-46152839 (-)
A/J MGP_AJ_G0032229
protein coding gene Chr7:45223969-45229680 (-)
AKR/J MGP_AKRJ_G0032165
protein coding gene Chr7:46495122-46500839 (-)
BALB/cJ MGP_BALBcJ_G0032241
protein coding gene Chr7:45223594-45229305 (-)
C3H/HeJ MGP_C3HHeJ_G0031956
protein coding gene Chr7:46978808-46984529 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032733
protein coding gene Chr7:48412012-48417729 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029747
protein coding gene Chr7:47774379-47780079 (-)
CAST/EiJ MGP_CASTEiJ_G0031284
protein coding gene Chr7:38422494-38428215 (-)
CBA/J MGP_CBAJ_G0031921
protein coding gene Chr7:50029469-50035186 (-)
DBA/2J MGP_DBA2J_G0032078
protein coding gene Chr7:44903460-44909181 (-)
FVB/NJ MGP_FVBNJ_G0032030
protein coding gene Chr7:44679933-44685650 (-)
LP/J MGP_LPJ_G0032157
protein coding gene Chr7:46854433-46860150 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032067
protein coding gene Chr7:48705107-48710824 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032748
protein coding gene Chr7:45698370-45704087 (-)
PWK/PhJ MGP_PWKPhJ_G0031007
protein coding gene Chr7:38274038-38279757 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030845
protein coding gene Chr7:33730443-33736166 (-)
WSB/EiJ MGP_WSBEiJ_G0031402
protein coding gene Chr7:46196357-46202074 (-)



Homology
more
  • Human Ortholog
    GRWD1, glutamate rich WD repeat containing 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    GRWD1, glutamate rich WD repeat containing 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CDW4, GRWD, RRB1, WDR28
  • Links
    NCBI Gene ID: 83743
    neXtProt AC: NX_Q9BQ67
    UniProt: Q9BQ67

  • Chr Location
    19q13.33; chr19:48445773-48453907 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 6644
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: GRWD1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000053801 Ensembl Gene Model | MGI Sequence Detail 5722 C57BL/6J ±  kb
transcript ENSMUST00000131384 Ensembl | MGI Sequence Detail 1974 Not Applicable  
polypeptide ENSMUSP00000116252 Ensembl | MGI Sequence Detail 446 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 57
    cDNA 57

    Microarray probesets 7
References
more
  • Summaries
    All 23
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 4
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory