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Alg8
Gene Detail
 Symbol
Name
ID
Alg8
asparagine-linked glycosylation 8 (alpha-1,3-glucosyltransferase)
MGI:2141959
Synonyms LOC381903, MGC:74399
Feature Type protein coding gene
Genetic Map
Chromosome 7
53.48 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:97371606-97392153 bp, + strand
From VEGA annotation of GRCm38

  20548 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:6931  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase/dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase
Gene Tree: Alg8

Human
homologs
Human Homolog ALG8, ALG8, alpha-1,3-glucosyltransferase
NCBI Gene ID 79053
neXtProt AC  NX_Q9BVK2
Human Synonyms  CDG1H
Human Chr (Location)  11q14.1; chr11:78100942-78139660 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human ALG8
Alleles
and
phenotypes
All alleles(16) : Targeted(1) Gene trapped(15)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process mannosylation, protein N-linked glycosylation
Component endoplasmic reticulum, endoplasmic reticulum membrane, ...
Function alpha-1,3-mannosyltransferase activity, transferase activity, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (95)    Tissues (95)    Images (7)
Theiler Stages: 22
Assay TypeResults
RNA in situ 95
cDNA source data(7)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(7) cDNA(7)
Microarray probesets(1)
Other database
links
VEGA Gene ModelOTTMUSG00000029538 (Evidence)
Ensembl Gene ModelENSMUSG00000035704 (Evidence)
Entrez Gene381903 (Evidence)
DFCITC1580179
DoTSDT.103557946, DT.111017098
NIA Mouse Gene IndexU155337
EC2.4.1.265
Consensus CDS ProjectCCDS52313.1
International Mouse Knockout Project StatusAlg8
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000029538 VEGA Gene Model | MGI Sequence Detail 20548 C57BL/6J ±  kb
transcript OTTMUST00000073211 VEGA | MGI Sequence Detail 2007 Not Applicable 
polypeptide OTTMUSP00000037871 VEGA | MGI Sequence Detail 526 Not Applicable 

For the selected sequences
All sequences(32) RefSeq(3) UniProt(2)
Polymorphisms SNPs within 2kb(279 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004856 Glycosyl transferase, ALG6/ALG8
Protein Ontology PR:000031475 probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase
References (Earliest) J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(33)
Other
accession IDs
MGI:2685935

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory