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Ino80e Gene Detail
Summary
  • Symbol
    Ino80e
  • Name
    INO80 complex subunit E
  • Synonyms
    Ccdc95
  • Feature Type
    protein coding gene
  • IDs
    MGI:2141881
    NCBI Gene: 233875
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:126851584-126862371 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 69.25 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    25 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2141881
protein coding gene Chr7:126850960-126862377 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033004
protein coding gene Chr7:131157361-131168778 (-)
A/J MGP_AJ_G0032987
protein coding gene Chr7:127676786-127688209 (-)
AKR/J MGP_AKRJ_G0032919
protein coding gene Chr7:130912091-130923508 (-)
BALB/cJ MGP_BALBcJ_G0032992
protein coding gene Chr7:127340298-127351715 (-)
C3H/HeJ MGP_C3HHeJ_G0032702
protein coding gene Chr7:130850251-130861668 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033498
protein coding gene Chr7:136257810-136269227 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030470
protein coding gene Chr7:128870699-128881886 (-)
CAST/EiJ MGP_CASTEiJ_G0032031
protein coding gene Chr7:122636181-122647640 (-)
CBA/J MGP_CBAJ_G0032675
protein coding gene Chr7:140844004-140857999 (-)
DBA/2J MGP_DBA2J_G0032827
protein coding gene Chr7:125652348-125663765 (-)
FVB/NJ MGP_FVBNJ_G0032780
protein coding gene Chr7:125502529-125514967 (-)
LP/J MGP_LPJ_G0032921
protein coding gene Chr7:132623526-132634943 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032812
protein coding gene Chr7:142014098-142026827 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033517
protein coding gene Chr7:129921903-129933326 (-)
PWK/PhJ MGP_PWKPhJ_G0031738
protein coding gene Chr7:118646748-118658251 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031584
protein coding gene Chr7:116767640-116779068 (-)
WSB/EiJ MGP_WSBEiJ_G0032143
protein coding gene Chr7:130901224-130912506 (-)



Homology
more
  • Human Ortholog
    INO80E, INO80 complex subunit E
  • Vertebrate Orthologs
    9
  • Human Ortholog
    INO80E, INO80 complex subunit E
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CCDC95
  • Links
    NCBI Gene ID: 283899
    neXtProt AC: NX_Q8NBZ0
    UniProt: Q8NBZ0

  • Chr Location
    16p11.2; chr16:29996209-30005794 (+)  GRCh38.p7

Human Diseases
less
  • References
    3 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    19 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 233875 NCBI Gene Model | MGI Sequence Detail 10788 C57BL/6J ±  kb
transcript NM_153580 RefSeq | MGI Sequence Detail 1143 FVB/N  
polypeptide NP_705808 RefSeq | MGI Sequence Detail 205 FVB/N  
For the selected sequence
Protein
Information
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  • UniProt
    11 Sequences
  • InterPro Domains
    IPR026678 INO80 complex subunit E
Molecular
Reagents
less
  • All nucleic 8
    cDNA 8

    Microarray probesets 1
Other
Accession IDs
less
MGI:2142073
References
more
  • Summaries
    All 38
    Diseases 3
    Gene Ontology 3
    Phenotypes 19
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:263550 Wang W, et al., Chemogenetic Activation of Prefrontal Cortex Rescues Synaptic and Behavioral Deficits in a Mouse Model of 16p11.2 Deletion Syndrome. J Neurosci. 2018 Jun 27;38(26):5939-5948

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory