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Phrf1 Gene Detail
Summary
  • Symbol
    Phrf1
  • Name
    PHD and ring finger domains 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2141847
    NCBI Gene: 101471
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:141228784-141262750 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 86.53 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    166 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2141847
protein coding gene Chr7:141228264-141262751 (+)
129S1/SvImJ MGP_129S1SvImJ_G0033218
protein coding gene Chr7:146406307-146442916 (+)
A/J MGP_AJ_G0033200
protein coding gene Chr7:142219375-142254372 (+)
AKR/J MGP_AKRJ_G0033132
protein coding gene Chr7:146141462-146183096 (+)
BALB/cJ MGP_BALBcJ_G0033201
protein coding gene Chr7:141960110-141998334 (+)
C3H/HeJ MGP_C3HHeJ_G0032915
protein coding gene Chr7:145895485-145941738 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033712
protein coding gene Chr7:151758884-151794437 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030685
protein coding gene Chr7:143429782-143463953 (+)
CAST/EiJ MGP_CASTEiJ_G0032245
protein coding gene Chr7:138205833-138241064 (+)
CBA/J MGP_CBAJ_G0032887
protein coding gene Chr7:156881459-156925272 (+)
DBA/2J MGP_DBA2J_G0033039
protein coding gene Chr7:140167988-140203113 (+)
FVB/NJ MGP_FVBNJ_G0032992
protein coding gene Chr7:140080698-140115368 (+)
LP/J MGP_LPJ_G0033134
protein coding gene Chr7:147901471-147941034 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033025
protein coding gene Chr7:157550751-157587394 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033732
protein coding gene Chr7:145118996-145157165 (+)
PWK/PhJ MGP_PWKPhJ_G0031949
protein coding gene Chr7:133447667-133481216 (+)
SPRET/EiJ MGP_SPRETEiJ_G0031796
protein coding gene Chr7:131943663-131980058 (+)
WSB/EiJ MGP_WSBEiJ_G0032356
protein coding gene Chr7:146066393-146101707 (+)



Homology
more
  • Human Ortholog
    PHRF1, PHD and ring finger domains 1
  • Vertebrate Orthologs
    7
  • Human Ortholog
    PHRF1, PHD and ring finger domains 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    PPP1R125, RNF221
  • Links
    NCBI Gene ID: 57661
    neXtProt AC: NX_Q9P1Y6
    UniProt: Q9P1Y6

  • Chr Location
    11p15.5; chr11:576446-612225 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000038611 Ensembl Gene Model | MGI Sequence Detail 33967 C57BL/6J ±  kb
transcript ENSMUST00000106027 Ensembl | MGI Sequence Detail 5248 Not Applicable  
polypeptide ENSMUSP00000101648 Ensembl | MGI Sequence Detail 1682 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 175
    Genomic 2
    cDNA 173

    Microarray probesets 4
References
more
  • Summaries
    All 34
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 11
  • Earliest
    J:65007 Cattanach BM, et al., Two imprinted gene mutations: three phenotypes. Hum Mol Genet. 2000 Sep 22;9(15):2263-73
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory