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Gcfc2 Gene Detail
Summary
  • Symbol
    Gcfc2
  • Name
    GC-rich sequence DNA binding factor 2
  • Synonyms
    AW146020
  • Feature Type
    protein coding gene
  • IDs
    MGI:2141656
    NCBI Gene: 330361
  • Gene Overview
    MyGene.info: GCFC2
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:81923635-81959098 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 35.81 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    383 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2141656
protein coding gene Chr6:81923635-81959915 (.)
129S1/SvImJ MGP_129S1SvImJ_G0030901
protein coding gene Chr6:82892406-82928577 (+)
A/J MGP_AJ_G0030870
protein coding gene Chr6:79701224-79737396 (+)
AKR/J MGP_AKRJ_G0030798
protein coding gene Chr6:81975360-82011553 (+)
BALB/cJ MGP_BALBcJ_G0030880
protein coding gene Chr6:79726500-79762687 (+)
C3H/HeJ MGP_C3HHeJ_G0030830
protein coding gene Chr6:102325873-102362450 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031340
protein coding gene Chr6:85132644-85168811 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028526
protein coding gene Chr6:78128685-78167077 (+)
CAST/EiJ MGP_CASTEiJ_G0029989
protein coding gene Chr6:81986215-82026843 (+)
CBA/J MGP_CBAJ_G0030567
protein coding gene Chr6:88519163-88557629 (+)
DBA/2J MGP_DBA2J_G0030720
protein coding gene Chr6:79001744-79037848 (+)
FVB/NJ MGP_FVBNJ_G0030673
protein coding gene Chr6:78257370-78294053 (+)
LP/J MGP_LPJ_G0030799
protein coding gene Chr6:82873776-82910862 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030709
protein coding gene Chr6:92840369-92884794 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031364
protein coding gene Chr6:81820261-81858937 (+)
PWK/PhJ MGP_PWKPhJ_G0029704
protein coding gene Chr6:77916973-77953886 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029532
protein coding gene Chr6:80683248-80722068 (+)
WSB/EiJ MGP_WSBEiJ_G0030070
protein coding gene Chr6:82252746-82291250 (+)



Homology
more
  • Human Ortholog
    GCFC2, GC-rich sequence DNA-binding factor 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    GCFC2, GC-rich sequence DNA-binding factor 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C2orf3, DNABF, GCF, TCF9
  • Links
    NCBI Gene ID: 6936
    neXtProt AC: NX_P16383
    UniProt: P16383

  • Chr Location
    2p12; chr2:75662655-75710986 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 2411
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 zebrafish;2 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: GCFC2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 330361 NCBI Gene Model | MGI Sequence Detail 35464 C57BL/6J ±  kb
transcript NM_177884 RefSeq | MGI Sequence Detail 3375 C57BL/6  
polypeptide Q8BKT3 UniProt | EBI | MGI Sequence Detail 769 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    Genomic 1
    cDNA 8

    Microarray probesets 5
References
more
  • Summaries
    All 27
    Gene Ontology 5
    Phenotypes 4
  • Earliest
    J:87486 Akeson EC, Chromosomal inversion discovered in C3H/HeJ mice. JAX Notes. 2003;491:15
  • Latest
    J:237754 Maga AM, et al., Quantitative trait loci affecting the 3D skull shape and size in mouse and prioritization of candidate genes in-silico. Front Physiol. 2015;6:92

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory