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Jazf1 Gene Detail
Summary
  • Symbol
    Jazf1
  • Name
    JAZF zinc finger 1
  • Synonyms
    Jaz1, Tip27
  • Feature Type
    protein coding gene
  • IDs
    MGI:2141450
    NCBI Gene: 231986
  • Gene Overview
    MyGene.info: JAZF1
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:52768797-53068631 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 25.74 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1671 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2141450
 protein coding gene Chr6:52768065-53068631 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030754
 protein coding gene Chr6:52059111-52370684 (-)
A/J MGP_AJ_G0030723
 protein coding gene Chr6:49626854-49927497 (-)
AKR/J MGP_AKRJ_G0030650
 protein coding gene Chr6:51350111-51653085 (-)
BALB/cJ MGP_BALBcJ_G0030735
 protein coding gene Chr6:49975352-50275495 (-)
C3H/HeJ MGP_C3HHeJ_G0030448
 protein coding gene Chr6:51352049-51661392 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031190
 protein coding gene Chr6:53206731-53518353 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028396
 protein coding gene Chr6:47261421-47564206 (-)
CAST/EiJ MGP_CASTEiJ_G0029851
 protein coding gene Chr6:51178743-51489210 (-)
CBA/J MGP_CBAJ_G0030422
 protein coding gene Chr6:55435523-55747502 (-)
DBA/2J MGP_DBA2J_G0030572
 protein coding gene Chr6:49536939-49836415 (-)
FVB/NJ MGP_FVBNJ_G0030524
 protein coding gene Chr6:49138301-49435592 (-)
LP/J MGP_LPJ_G0030657
 protein coding gene Chr6:52018516-52326136 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030558
 protein coding gene Chr6:58040083-58346466 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031220
 protein coding gene Chr6:51288373-51588444 (-)
PWK/PhJ MGP_PWKPhJ_G0029564
 protein coding gene Chr6:49165981-49470697 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029398
 protein coding gene Chr6:50614556-50935113 (-)
WSB/EiJ MGP_WSBEiJ_G0029928
 protein coding gene Chr6:51285766-51589995 (-)



Homology
more
  • Human Ortholog
    JAZF1, JAZF zinc finger 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    JAZF1, JAZF zinc finger 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    TIP27, ZNF802
  • Links
    NCBI Gene ID: 221895
    neXtProt AC: NX_Q86VZ6
    UniProt: Q86VZ6

  • Chr Location
    7p15.2-p15.1; chr7:27830573-28180818 (-)  GRCh38.p7
  • HomoloGene
    Vertebrate Homology Class 18291
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: JAZF1
  • Gene Tree
    Jazf1
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    99
  • Tissues
    48
  • cDNA Data
    25
  • Literature Summary
    9
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000063568 Ensembl Gene Model | MGI Sequence Detail 299835 C57BL/6J ±  kb
transcript ENSMUST00000074541 Ensembl | MGI Sequence Detail 2203 Not Applicable  
polypeptide ENSMUSP00000074129 Ensembl | MGI Sequence Detail 243 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 26
    cDNA 25
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 46
    Developmental Gene Expression 9
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:276200 Meng F, et al., JAZF1 Inhibits Adipose Tissue Macrophages and Adipose Tissue Inflammation in Diet-Induced Diabetic Mice. Biomed Res Int. 2018;2018:4507659
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/08/2019
MGI 6.14 		The Jackson Laboratory