About   Help   FAQ
Fam185a Gene Detail
Summary
  • Symbol
    Fam185a
  • Name
    family with sequence similarity 185, member A
  • Feature Type
    protein coding gene
  • IDs
    MGI:2140983
    NCBI Gene: 330050
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:21629956-21687122 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 9.83 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    2200 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2140983
 protein coding gene Chr5:21629861-21693269 (+)
129S1/SvImJ ENSMUSG00200010644
 protein coding gene Chr5:17264125-17321299 (+)
A/J ENSMUSG00195039552
 protein coding gene Chr5:16749922-16807090 (+)
AKR/J ENSMUSG00220036826
 protein coding gene Chr5:16784529-16841699 (+)
BALB/cJ ENSMUSG00180023297
 protein coding gene Chr5:16596145-16653314 (+)
C3H/HeJ ENSMUSG00175027031
 protein coding gene Chr5:18558145-18615311 (+)
C57BL/6NJ ENSMUSG00215013868
 protein coding gene Chr5:17163656-17220824 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026986
 protein coding gene Chr5:16421644-16478059 (+)
CAST/EiJ ENSTCUG00005003363
 protein coding gene Chr5:16824205-16881161 (+)
CBA/J ENSMUSG00210005005
 protein coding gene Chr5:17592340-17649506 (+)
DBA/2J ENSMUSG00185016647
 protein coding gene Chr5:19074220-19131386 (+)
FVB/NJ ENSMUSG00205023068
 protein coding gene Chr5:16295029-16352197 (+)
JF1/MsJ ENSUMUG00000004094
 protein coding gene Chr5:23664857-23728303 (+)
LP/J ENSMUSG00230024218
 protein coding gene Chr5:23546461-23603632 (+)
NOD/ShiLtJ ENSMUSG00190004587
 protein coding gene Chr5:16602376-16659542 (+)
NZO/HlLtJ ENSMUSG00225008518
 protein coding gene Chr5:28937516-28994683 (+)
PWK/PhJ ENSLUMG00010035316
 protein coding gene Chr5:16699896-16763480 (+)
SPRET/EiJ ENSMSPG00010028127
 protein coding gene Chr5:17588551-17651345 (+)
WSB/EiJ ENSIUOG00005031594
 protein coding gene Chr5:19412120-19469328 (+)



Homology
more
  • Human Ortholog
    FAM185A, family with sequence similarity 185 member A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FAM185A, family with sequence similarity 185 member A
  • Links
    NCBI Gene ID: 222234
    UniProt: Q8N0U4

  • Chr Location
    7q22.1; chr7:102748969-102850723 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotypes from 1 allele in 1 genetic background
    17 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    599
  • Tissues
    2
  • cDNA Data
    25
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000047221 Ensembl Gene Model | MGI Sequence Detail 57167 C57BL/6J ±  kb
    transcript ENSMUST00000056045 Ensembl | MGI Sequence Detail 3027 Not Applicable  
    polypeptide ENSMUSP00000058333 Ensembl | MGI Sequence Detail 378 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 26
      Genomic 1
      cDNA 25

      Microarray probesets 3
    References
    more
    • Summaries
      All 35
      Developmental Gene Expression 1
      Diseases 1
      Phenotypes 17
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory