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Dcun1d4 Gene Detail
Summary
  • Symbol
    Dcun1d4
  • Name
    defective in cullin neddylation 1 domain containing 4
  • Synonyms
    DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae)
  • Feature Type
    protein coding gene
  • IDs
    MGI:2140972
    NCBI Gene: 100737
  • Alliance
    gene page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:73638353-73718137 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 38.85 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    4446 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2140972
 protein coding gene Chr5:73638343-73718137 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029626
 protein coding gene Chr5:73495196-73577065 (+)
A/J MGP_AJ_G0029594
 protein coding gene Chr5:70728074-70812181 (+)
AKR/J MGP_AKRJ_G0029542
 protein coding gene Chr5:73015577-73115716 (+)
BALB/cJ MGP_BALBcJ_G0029603
 protein coding gene Chr5:71440057-71524230 (+)
C3H/HeJ MGP_C3HHeJ_G0029326
 protein coding gene Chr5:73420144-73505865 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030057
 protein coding gene Chr5:76510424-76594897 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027297
 protein coding gene Chr5:66419551-66499067 (+)
CAST/EiJ MGP_CASTEiJ_G0028734
 protein coding gene Chr5:72488670-72577065 (+)
CBA/J MGP_CBAJ_G0029295
 protein coding gene Chr5:79016262-79105888 (+)
DBA/2J MGP_DBA2J_G0029440
 protein coding gene Chr5:70803504-70889808 (+)
FVB/NJ MGP_FVBNJ_G0029401
 protein coding gene Chr5:69952522-70033986 (+)
LP/J MGP_LPJ_G0029526
 protein coding gene Chr5:73937614-74021036 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029428
 protein coding gene Chr5:82291997-82373730 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030090
 protein coding gene Chr5:72565771-72650545 (+)
PWK/PhJ MGP_PWKPhJ_G0028457
 protein coding gene Chr5:69780407-69864531 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028292
 protein coding gene Chr5:71926804-72008987 (+)
WSB/EiJ MGP_WSBEiJ_G0028814
 protein coding gene Chr5:72865384-72949934 (+)



Homology
more
  • Human Ortholog
    DCUN1D4, defective in cullin neddylation 1 domain containing 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DCUN1D4, defective in cullin neddylation 1 domain containing 4
  • Synonyms
    DCNL4
  • Links
    NCBI Gene ID: 23142
    UniProt: Q92564

  • Chr Location
    4q12; chr4:51833884-51916837 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    372 phenotype references
  • All Mutations and Alleles
    16
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    2
  • Gene trapped
    8
  • Radiation induced
    1
  • Spontaneous
    3
  • Genomic Mutations
    6 involving Dcun1d4
  • Incidental Mutations
    Mutagenetix
  • Find Mice (IMSR)
    33 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    885
  • Tissues
    104
  • cDNA Data
    90
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 100737 NCBI Gene Model | MGI Sequence Detail 79785 C57BL/6J ±  kb
transcript NR_153313 RefSeq | MGI Sequence Detail 4209 C57BL/6  
polypeptide Q8CCA0 UniProt | EBI | MGI Sequence Detail 292 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 92
    cDNA 90
    Primer pair 2

    Microarray probesets 5
References
more
  • Summaries
    All 401
    Developmental Gene Expression 5
    Diseases 1
    Gene Ontology 7
    Phenotypes 372
  • Earliest
    J:5021 Batchelor AL, et al., A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia. Mutat Res. 1966 Jun;3(3):218-29
  • Latest
    J:364920 Abdullah NS, et al., Early life microbiota colonization programs nociceptor sensitivity by regulating NGF production in mast cells. Mucosal Immunol. 2025 Apr;18(2):326-338
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory