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Dcun1d4 Gene Detail
Summary
  • Symbol
    Dcun1d4
  • Name
    DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae)
  • Feature Type
    protein coding gene
  • IDs
    MGI:2140972
    NCBI Gene: 100737
  • Gene Overview
    MyGene.info: DCUN1D4
Location & Maps
more
  • Sequence Map
    Chr5:73481000-73560794 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      79795 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 38.85 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    DCUN1D4, defective in cullin neddylation 1 domain containing 4
  • Vertebrate Orthologs
    7
  • Human Ortholog
    DCUN1D4, defective in cullin neddylation 1 domain containing 4
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 23142
    neXtProt AC: NX_Q92564

  • Chr Location
    4q12; chr4:51843000-51916837 (+)  GRCh38.p2
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    232 phenotype references
  • All Mutations and Alleles
    18
  • Chemically induced (other)
    2
  • Gene trapped
    12
  • Radiation induced
    1
  • Spontaneous
    3
  • Genomic Mutations
    6 involving Dcun1d4
  • Incidental Mutations
    Mutagenetix
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    172
  • Tissues
    99
  • cDNA Data
    89
  • Literature Summary
    4
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024911 VEGA Gene Model | MGI Sequence Detail 79795 C57BL/6J ±  kb
transcript OTTMUST00000061359 VEGA | MGI Sequence Detail 4117 Not Applicable  
polypeptide OTTMUSP00000030082 VEGA | MGI Sequence Detail 306 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    686 from dbSNP Build 142
Protein
Information
less
  • UniProt
    10 Sequences
  • Protein Ontology
    PR:000006333 DCN1-like protein 4
  • InterPro Domains
    IPR014764 Defective-in-cullin neddylation protein
    IPR005176 Potentiating neddylation domain
Molecular
Reagents
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  • All nucleic 91
    cDNA 89
    Primer pair 2

    Microarray probesets 5
References
more
  • Summaries
    All 26
    Developmental Gene Expression 4
    Diseases 1
    Gene Ontology 2
    Phenotypes 232
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/27/2016
MGI 6.05 		The Jackson Laboratory