Mapre3
Gene Detail

Symbol

Name
ID

Mapre3
microtubule-associated protein, RP/EB family, member 3
MGI:2140967

Synonyms

EB3

Feature Type

protein coding gene

Genetic Map

Chromosome 5
16.90 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr5:30814641-30866106 bp, + strand From VEGA annotation of GRCm38   51466 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate
homology

HomoloGene:56565  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 cattle; 1 dog; 1 chicken

Gene Tree: Mapre3

Human
homologs

Human Homolog		MAPRE3, microtubule-associated protein, RP/EB family, member 3
NCBI Gene ID		22924
neXtProt AC		NX_Q9UPY8
Human Synonyms		EB3, EBF3, EBF3-S, RP3
Human Chr (Location)		2p23.3-p23.1; chr2:26970657-27027219 (+)  GRCh38

Mutations,
alleles, and
phenotypes

All mutations/alleles(8) : Gene trapped(2) Radiation induced(3) Targeted(3)
Genomic Mutations involving Mapre3 (3)
Incidental mutations (data from APF )
Mutations Annotated to Human Diseases (1)    Phenotype Images(4)

Interactions

Mapre3 interacts with 173 markers (Mir16-1, Mir17, Mir19a, ...)

View All

Gene Ontology
(GO)
classifications

All GO classifications: (20 annotations)

Process	cell cycle, cell division, ...
Component	cytoplasm, cytoplasmic microtubule, ...
Function	microtubule binding, protein binding

External Resources: FuncBase

Expression

Literature Summary: (1 records)

cDNA source data(2)
External Resources: Allen Institute   GEO   Expression Atlas

Molecular
reagents

All nucleic(2) cDNA(2)
Microarray probesets(4)

Other database
links

VEGA Gene Model	OTTMUSG00000022303 (Evidence)
Ensembl Gene Model	ENSMUSG00000029166 (Evidence)
Entrez Gene	100732 (Evidence)
DFCI	TC1576280, TC1604063
DoTS	DT.101724334, DT.101293123
NIA Mouse Gene Index	U005425
Consensus CDS Project	CCDS19163.1
International Mouse Knockout Project Status	Mapre3

Sequences

Length	Strain/Species
genomic	OTTMUSG00000022303	VEGA Gene Model | MGI Sequence Detail	51466	C57BL/6J
transcript	OTTMUST00000053142	VEGA | MGI Sequence Detail	2021	Not Applicable
polypeptide	OTTMUSP00000025251	VEGA | MGI Sequence Detail	281	Not Applicable

All sequences(49) RefSeq(9) UniProt(7)

Polymorphisms

SNPs within 2kb(286 from dbSNP Build 137)

Protein-related
information

Resource	ID	Description
InterPro	IPR001715	Calponin homology domain
InterPro	IPR004953	EB1, C-terminal
InterPro	IPR027328	Microtubule-associated protein RP/EB
Protein Ontology	PR:000010172	microtubule-associated protein RP/EB family member 3

References

(Earliest) J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
(Latest) J:212241 Boutin C, et al., A dual role for planar cell polarity genes in ciliated cells. Proc Natl Acad Sci U S A. 2014 Jul 29;111(30):E3129-38
All references(34)