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Mapre3
Gene Detail
Symbol

Name
ID
Mapre3
microtubule-associated protein, RP/EB family, member 3
MGI:2140967
Synonyms
EB3
Feature Type
protein coding gene
Genetic Map
Chromosome 5
16.90 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr5:30814641-30866106 bp, + strand
From VEGA annotation of GRCm38

  51466 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:56565  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 cattle; 1 dog; 1 chicken

HCOP human homology predictions: MAPRE3
Gene Tree: Mapre3

Human
homologs
MAPRE3, microtubule-associated protein, RP/EB family, member 3
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 22924
neXtProt AC: NX_Q9UPY8

Human Synonyms: EB3, EBF3, EBF3-S, RP3

Human Chr (Location): 2p23.3-p23.1; chr2:26970371-27027219 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(8) : Gene trapped(2) Radiation induced(3) Targeted(3)
Genomic Mutations involving Mapre3 (3)
Incidental mutations (data from APF , CvDC )
Mutations Annotated to Human Diseases (1)    Phenotype Images(4)
Interactions
Mapre3 interacts with 173 markers (Mir16-1, Mir17, Mir19a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (21 annotations)
Process cell cycle, cell division, ...
Component cytoplasm, cytoplasmic microtubule, ...
Function microtubule binding, protein binding
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(2)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: ZFIN mapre3b    NEW 
Molecular
reagents
All nucleic(2) cDNA(2)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000022303 (Evidence)
Ensembl Gene Model ENSMUSG00000029166 (Evidence)
Entrez Gene 100732 (Evidence)
DFCI TC1604063, TC1576280
DoTS DT.101724334, DT.101293123
NIA Mouse Gene Index U005425
Consensus CDS Project CCDS19163.1
International Mouse Phenotyping Consortium Status Mapre3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022303 VEGA Gene Model | MGI Sequence Detail 51466 C57BL/6J ±  kb
transcript OTTMUST00000053142 VEGA | MGI Sequence Detail 2021 Not Applicable 
polypeptide OTTMUSP00000025251 VEGA | MGI Sequence Detail 281 Not Applicable 

For the selected sequences
All sequences(50) RefSeq(9) UniProt(4)
Polymorphisms
SNPs within 2kb(286 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001715 Calponin homology domain
InterPro IPR004953 EB1, C-terminal
InterPro IPR027328 Microtubule-associated protein RP/EB
Protein Ontology PR:000010172 microtubule-associated protein RP/EB family member 3
References
(Earliest) J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
(Latest) J:212241 Boutin C, et al., A dual role for planar cell polarity genes in ciliated cells. Proc Natl Acad Sci U S A. 2014 Jul 29;111(30):E3129-38
All references(33)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/30/2015
MGI 5.22
The Jackson Laboratory