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Tent2 Gene Detail
Summary
  • Symbol
    Tent2
  • Name
    terminal nucleotidyltransferase 2
  • Synonyms
    8030446C20Rik, Papd4
  • Feature Type
    protein coding gene
  • IDs
    MGI:2140950
    NCBI Gene: 100715
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:93146282-93192385 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 47.81 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    190 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2140950
protein coding gene Chr13:93145855-93192435 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020823
protein coding gene Chr13:94481271-94529133 (-)
A/J MGP_AJ_G0020777
protein coding gene Chr13:90967467-91018893 (-)
AKR/J MGP_AKRJ_G0020750
protein coding gene Chr13:93733921-93779788 (-)
BALB/cJ MGP_BALBcJ_G0020773
protein coding gene Chr13:91627257-91672090 (-)
C3H/HeJ MGP_C3HHeJ_G0020567
protein coding gene Chr13:93435253-93480770 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021210
protein coding gene Chr13:97363500-97409672 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018777
protein coding gene Chr13:86871837-86916788 (-)
CAST/EiJ MGP_CASTEiJ_G0020086
protein coding gene Chr13:92694924-92741437 (-)
CBA/J MGP_CBAJ_G0020526
protein coding gene Chr13:101211764-101270917 (-)
DBA/2J MGP_DBA2J_G0020651
protein coding gene Chr13:90756611-90801622 (-)
FVB/NJ MGP_FVBNJ_G0020631
protein coding gene Chr13:89552702-89597519 (-)
LP/J MGP_LPJ_G0020724
protein coding gene Chr13:94594112-94640882 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020660
protein coding gene Chr13:101690290-101762872 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021250
protein coding gene Chr13:93131449-93177850 (-)
PWK/PhJ MGP_PWKPhJ_G0019838
protein coding gene Chr13:89458243-89510192 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019662
protein coding gene Chr13:89402591-89454942 (-)
WSB/EiJ MGP_WSBEiJ_G0020143
protein coding gene Chr13:93622559-93669704 (-)



Homology
more
  • Human Ortholog
    TENT2, terminal nucleotidyltransferase 2
  • Vertebrate Orthologs
    11
  • Human Ortholog
    TENT2, terminal nucleotidyltransferase 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    APD4, GLD2, PAPD4, TUT2
  • Links
    NCBI Gene ID: 167153
    neXtProt AC: NX_Q6PIY7
    UniProt: Q6PIY7

  • Chr Location
    5q14.1; chr5:79612416-79686648 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 44022
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;2 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: TENT2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele reuslts in disruption in polyadenylation in oocytes and somatic cells.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000042167 Ensembl Gene Model | MGI Sequence Detail 46104 C57BL/6J ±  kb
transcript ENSMUST00000048702 Ensembl | MGI Sequence Detail 2990 Not Applicable  
polypeptide ENSMUSP00000048124 Ensembl | MGI Sequence Detail 484 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 7
    cDNA 7

    Microarray probesets 5
References
more
  • Summaries
    All 38
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 10
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:215954 Cragle C, et al., Musashi protein-directed translational activation of target mRNAs is mediated by the poly(A) polymerase, germ line development defective-2. J Biol Chem. 2014 May 16;289(20):14239-51

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
12/03/2019
MGI 6.14
The Jackson Laboratory