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Lin54 Gene Detail
Summary
  • Symbol
    Lin54
  • Name
    lin-54 homolog (C. elegans)
  • Feature Type
    protein coding gene
  • IDs
    MGI:2140902
    NCBI Gene: 231506
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr5:100441918-100500639 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      58722 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 48.48 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    LIN54, lin-54 DREAM MuvB core complex component
  • Vertebrate Orthologs
    10
  • Human Ortholog
    LIN54, lin-54 DREAM MuvB core complex component
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CXCDC1, JC8.6, MIP120, TCX1
  • Links
    NCBI Gene ID: 132660
    neXtProt AC: NX_Q6MZP7
    UniProt: Q6MZP7

  • Chr Location
    4q21.22; chr4:82924603-83012951 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 18212
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: LIN54
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000033912 VEGA Gene Model | MGI Sequence Detail 58722 C57BL/6J ±  kb
transcript OTTMUST00000085557 VEGA | MGI Sequence Detail 4592 Not Applicable  
polypeptide OTTMUSP00000046234 VEGA | MGI Sequence Detail 749 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    177 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 51
    cDNA 51

    Microarray probesets 5
References
more
  • Summaries
    All 31
    Gene Ontology 1
    Phenotypes 12
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/07/2017
MGI 6.11
The Jackson Laboratory