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Lin54 Gene Detail
Summary
  • Symbol
    Lin54
  • Name
    lin-54 homolog (C. elegans)
  • Feature Type
    protein coding gene
  • IDs
    MGI:2140902
    NCBI Gene: 231506
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:100442033-100500649 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 48.48 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    177 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2140902
protein coding gene Chr5:100441918-100500649 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029786
protein coding gene Chr5:101925359-101985805 (-)
A/J MGP_AJ_G0029752
protein coding gene Chr5:98132939-98192094 (-)
AKR/J MGP_AKRJ_G0029698
protein coding gene Chr5:101365755-101425555 (-)
BALB/cJ MGP_BALBcJ_G0029762
protein coding gene Chr5:99163174-99226243 (-)
C3H/HeJ MGP_C3HHeJ_G0029485
protein coding gene Chr5:101714825-101774477 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030217
protein coding gene Chr5:106156839-106234735 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027452
protein coding gene Chr5:93368588-93428503 (-)
CAST/EiJ MGP_CASTEiJ_G0028896
protein coding gene Chr5:100367666-100428900 (-)
CBA/J MGP_CBAJ_G0029455
protein coding gene Chr5:109839689-109911643 (-)
DBA/2J MGP_DBA2J_G0029599
protein coding gene Chr5:98320932-98384113 (-)
FVB/NJ MGP_FVBNJ_G0029558
protein coding gene Chr5:97126100-97183866 (-)
LP/J MGP_LPJ_G0029687
protein coding gene Chr5:102539600-102601081 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029587
protein coding gene Chr5:114925681-114996972 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030250
protein coding gene Chr5:100846737-100908184 (-)
PWK/PhJ MGP_PWKPhJ_G0028614
protein coding gene Chr5:96753283-96814927 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028449
protein coding gene Chr5:98509100-98582422 (-)
WSB/EiJ MGP_WSBEiJ_G0028974
protein coding gene Chr5:101181005-101243326 (-)



Homology
more
  • Human Ortholog
    LIN54, lin-54 DREAM MuvB core complex component
  • Vertebrate Orthologs
    10
  • Human Ortholog
    LIN54, lin-54 DREAM MuvB core complex component
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CXCDC1, JC8.6, MIP120, TCX1
  • Links
    NCBI Gene ID: 132660
    neXtProt AC: NX_Q6MZP7
    UniProt: Q6MZP7

  • Chr Location
    4q21.22; chr4:82924603-83012951 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 18212
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: LIN54
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 231506 NCBI Gene Model | MGI Sequence Detail 58617 C57BL/6J ±  kb
transcript NM_001115010 RefSeq | MGI Sequence Detail 4596 C57BL/6  
polypeptide Q571G4 UniProt | EBI | MGI Sequence Detail 749 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 52
    cDNA 52

    Microarray probesets 5
References
more
  • Summaries
    All 31
    Gene Ontology 1
    Phenotypes 12
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory