Oas1d
Gene Detail

Symbol Name ID

Oas1d 2'-5' oligoadenylate synthetase 1D MGI:2140770

Feature Type

protein coding gene

Genetic Map

Chromosome 5

60.87 cM, cytoband F
Detailed Genetic Map ± 1 cM


Mapping data(4)

Sequence Map

Chr5:120914536-120921652 bp, + strand From VEGA annotation of GRCm38   7117 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:110815  Vertebrate Homology Class
3 mouse; 2 rat

Protein SuperFamily: oligo(A) synthetase
Gene Tree: Oas1d

Alleles and phenotypes

All alleles(5) : Targeted(3) Gene trapped(2)
 

Homozygous null females exhibit reduced fertility due to defects in ovarian follicle development and decreased efficiency of ovulation.

 

Gene Ontology (GO) classifications

All GO classifications: (9 annotations)

Process	embryo development, negative regulation of transferase activity, ...
Component	cytoplasm
Function	double-stranded RNA binding, enzyme inhibitor activity, ...

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (17)    Tissues (12)    Images (2)
Theiler Stages: 20, 22, 25, 28

Assay Type	Results
RT-PCR	17

cDNA source data(74)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(76) Genomic(1) cDNA(74) Primer pair(1)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000025364 (Evidence)
Ensembl Gene Model	ENSMUSG00000032623 (Evidence)
Entrez Gene	100535 (Evidence)
UniGene	247620
DoTS	DT.91355379, DT.94289713
NIA Mouse Gene Index	U006114
Consensus CDS Project	CCDS19631.1
International Mouse Knockout Project Status	Oas1d

Sequences

Length	Strain/Species
genomic	OTTMUSG00000025364	VEGA Gene Model | MGI Sequence Detail	7117	C57BL/6J
transcript	OTTMUST00000062444	VEGA | MGI Sequence Detail	2021	Not Applicable
polypeptide	OTTMUSP00000030778	VEGA | MGI Sequence Detail	361	Not Applicable

All sequences(27) RefSeq(2) UniProt(4)

Protein-related information

Resource	ID	Description
InterPro	IPR018952	2'-5'-oligoadenylate synthetase 1, domain 2/C-terminal
InterPro	IPR006116	2-5-oligoadenylate synthetase, N-terminal

References

(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:192649 Kristiansen H, et al., The oligoadenylate synthetase family: an ancient protein family with multiple antiviral activities. J Interferon Cytokine Res. 2011 Jan;31(1):41-7
All references(30)

Other accession IDs

MGI:2141327