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Oas1d
Gene Detail
 Symbol
Name
ID
Oas1d
2'-5' oligoadenylate synthetase 1D
MGI:2140770
Feature Type protein coding gene
Genetic Map
Chromosome 5
60.87 cM, cytoband F
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr5:120914536-120921652 bp, + strand
From VEGA annotation of GRCm38

  7117 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:110815  Vertebrate Homology Class
3 mouse

Protein SuperFamily: oligo(A) synthetase
Gene Tree: Oas1d

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(2) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous null females exhibit reduced fertility due to defects in ovarian follicle development and decreased efficiency of ovulation.
 
Interactions
Oas1d interacts with 106 markers (Mir19a, Mir19b-1, Mir19b-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process embryo development, negative regulation of transferase activity, ...
Component cytoplasm
Function double-stranded RNA binding, enzyme inhibitor activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (17)    Tissues (12)    Images (2)
Theiler Stages: 20, 22, 25, 27
Assay TypeResults
RT-PCR 17
cDNA source data(81)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(83) Genomic(1) cDNA(81) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000025364 (Evidence)
Ensembl Gene ModelENSMUSG00000032623 (Evidence)
Entrez Gene100535 (Evidence)
UniGene247620
DoTSDT.91355379, DT.94289713
NIA Mouse Gene IndexU006114
Consensus CDS ProjectCCDS19631.1
International Mouse Knockout Project StatusOas1d
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025364 VEGA Gene Model | MGI Sequence Detail 7117 C57BL/6J ±  kb
transcript OTTMUST00000062444 VEGA | MGI Sequence Detail 2021 Not Applicable 
polypeptide OTTMUSP00000030778 VEGA | MGI Sequence Detail 361 Not Applicable 

For the selected sequences
All sequences(27) RefSeq(2) UniProt(4)
Polymorphisms SNPs within 2kb(1 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR026774 2'-5'-oligoadenylate synthase
InterPro IPR018952 2'-5'-oligoadenylate synthetase 1, domain 2/C-terminal
InterPro IPR006116 2-5-oligoadenylate synthetase, N-terminal
References (Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:192649 Kristiansen H, et al., The oligoadenylate synthetase family: an ancient protein family with multiple antiviral activities. J Interferon Cytokine Res. 2011 Jan;31(1):41-7
All references(30)
Other
accession IDs
MGI:2141327

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory