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Phf24 Gene Detail
Summary
  • Symbol
    Phf24
  • Name
    PHD finger protein 24
  • Synonyms
    GINIP, mKIAA1045, N28178
  • Feature Type
    protein coding gene
  • IDs
    MGI:2140712
    NCBI Gene: 230085
  • Alliance
    genome feature page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:42916660-42944752 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 22.91 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    731 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2140712
 protein coding gene Chr4:42872619-42944752 (+)
129S1/SvImJ ENSMUSG00200004289
 protein coding gene Chr4:38969436-38980758 (+)
A/J ENSMUSG00195003198
 protein coding gene Chr4:39452127-39463449 (+)
AKR/J ENSMUSG00220031974
 protein coding gene Chr4:39135878-39147200 (+)
BALB/cJ ENSMUSG00180024835
 protein coding gene Chr4:39038902-39050224 (+)
C3H/HeJ ENSMUSG00175022748
 protein coding gene Chr4:39183248-39194570 (+)
C57BL/6NJ ENSMUSG00215015977
 protein coding gene Chr4:38950450-38961772 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025922
 protein coding gene Chr4:37022779-37045168 (+)
CAST/EiJ ENSTCUG00005004322
 protein coding gene Chr4:39217222-39228571 (+)
CBA/J ENSMUSG00210007185
 protein coding gene Chr4:38869599-38880921 (+)
DBA/2J ENSMUSG00185006249
 protein coding gene Chr4:39233065-39244387 (+)
FVB/NJ ENSMUSG00205019299
 protein coding gene Chr4:38476283-38487605 (+)
JF1/MsJ ENSUMUG00000012109
 protein coding gene Chr4:39477361-39488516 (+)
LP/J ENSMUSG00230040481
 protein coding gene Chr4:42781404-42792727 (+)
NOD/ShiLtJ ENSMUSG00190005184
 protein coding gene Chr4:39094243-39105565 (+)
NZO/HlLtJ ENSMUSG00225006811
 protein coding gene Chr4:47381082-47392404 (+)
PWK/PhJ ENSLUMG00010006220
 protein coding gene Chr4:38472571-38488616 (+)
SPRET/EiJ ENSMSPG00010023926
 protein coding gene Chr4:39403187-39414166 (+)
WSB/EiJ ENSIUOG00005048877
 protein coding gene Chr4:38847177-38858499 (+)



Homology
more
  • Human Ortholog
    PHF24, PHD finger protein 24
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PHF24, PHD finger protein 24
  • Synonyms
    GINIP
  • Links
    NCBI Gene ID: 23349
    UniProt: Q9UPV7

  • Chr Location
    9p13.3; chr9:34665607-34982544 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from multigenic genotypes
    17 phenotype references
Mice homozygous for a knock-out allele develop a selective and prolonged mechanical hypersensitivity in models of inflammation and neuropathy and show impaired baclofen-mediated analgesia following nerve injury.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    791
  • Tissues
    57
  • cDNA Data
    41
  • Literature Summary
    4
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000036062 Ensembl Gene Model | MGI Sequence Detail 28093 C57BL/6J ±  kb
transcript ENSMUST00000107975 Ensembl | MGI Sequence Detail 6494 Not Applicable  
polypeptide ENSMUSP00000103609 Ensembl | MGI Sequence Detail 400 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 43
    cDNA 41
    Primer pair 2

    Microarray probesets 6
References
more
  • Summaries
    All 42
    Developmental Gene Expression 4
    Gene Ontology 3
    Phenotypes 17
  • Earliest
    J:83413 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003 Feb 28;10(1):35-48
  • Latest
    J:389403 Voisin T, et al., Skin inflammation and itch response are independently regulated by distinct nociceptor subsets. Immunity. 2026 Apr 15;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory