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Pramel12 Gene Detail
Summary
  • Symbol
    Pramel12
  • Name
    PRAME like 12
  • Synonyms
    4732496O08Rik, Pramef8
  • Feature Type
    protein coding gene
  • IDs
    MGI:2140473
    NCBI Gene: 242736
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:143412426-143421091 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 77.65 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    103 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2140473
protein coding gene Chr4:143412155-143421091 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029069
protein coding gene Chr4:146641348-146649822 (+)
A/J MGP_AJ_G0029029
protein coding gene Chr4:140251265-140259928 (+)
AKR/J MGP_AKRJ_G0028981
protein coding gene Chr4:144299813-144308465 (+)
BALB/cJ MGP_BALBcJ_G0029053
protein coding gene Chr4:140918954-140927619 (+)
C3H/HeJ MGP_C3HHeJ_G0028767
protein coding gene Chr4:144675013-144683680 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029494
protein coding gene Chr4:151672798-151681465 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026764
protein coding gene Chr4:133093996-133102945 (+)
CAST/EiJ MGP_CASTEiJ_G0028199
protein coding gene Chr4:142975841-142984462 (+)
CBA/J MGP_CBAJ_G0028731
protein coding gene Chr4:156230006-156238684 (+)
DBA/2J MGP_DBA2J_G0028881
protein coding gene Chr4:140594799-140603451 (+)
FVB/NJ MGP_FVBNJ_G0028848
protein coding gene Chr4:139762361-139771008 (+)
LP/J MGP_LPJ_G0028980
protein coding gene Chr4:146674410-146683078 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028874
protein coding gene Chr4:159883738-159892389 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029532
protein coding gene Chr4:144843746-144852409 (+)
PWK/PhJ MGP_PWKPhJ_G0027921
protein coding gene Chr4:137518674-137527338 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027744
protein coding gene Chr4:140664719-140673886 (+)
WSB/EiJ MGP_WSBEiJ_G0028277
protein coding gene Chr4:145144068-145152726 (+)



Homology
more
  • Human Ortholog
    PRAMEF7, PRAME family member 7
  • Vertebrate Orthologs
    24
  • Human Ortholog
    PRAMEF7, PRAME family member 7
    Orthology source: HomoloGene
  • Links
    NCBI Gene ID: 441871
    neXtProt AC: NX_Q5VXH5
    UniProt: Q5VXH5

  • Chr Location
    1p36.21; chr1:12916647-12920480 (+)  GRCh38.p7

  • Human Ortholog
    PRAMEF8, PRAME family member 8
    Orthology source: HomoloGene
  • Synonyms
    PRAMEF24
  • Links
    NCBI Gene ID: 391002
    neXtProt AC: NX_Q5VWM4
    UniProt: Q5VWM4

  • Chr Location
    1p36.21; chr1:13281223-13285137 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000046862 Ensembl Gene Model | MGI Sequence Detail 8666 C57BL/6J ±  kb
    transcript ENSMUST00000059790 Ensembl | MGI Sequence Detail 3886 Not Applicable  
    polypeptide ENSMUSP00000058676 Ensembl | MGI Sequence Detail 480 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      3 Sequences
    • InterPro Domains
      IPR032675 Leucine-rich repeat domain superfamily
      IPR026271 PRAME family
    Molecular
    Reagents
    less
    • All nucleic 7
      cDNA 7

      Microarray probesets 6
    References
    more
    • Summaries
      All 27
      Gene Ontology 1
      Phenotypes 9
    • Earliest
      J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
    • Latest
      J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    last database update
    02/16/2021
    MGI 6.16
    The Jackson Laboratory