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AI481877 Gene Detail
Summary
  • Symbol
    AI481877
  • Name
    expressed sequence AI481877
  • Synonyms
    Gm426, LOC242489, Shoc1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2140313
    NCBI Gene: 100155
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr4:59043753-59138983 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      95231 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 32.36 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    C9orf84, chromosome 9 open reading frame 84
  • Vertebrate Orthologs
    9
  • Human Ortholog
    C9orf84, chromosome 9 open reading frame 84
    Orthology source: HomoloGene, HGNC
  • Synonyms
    SHOC1, ZIP2, ZIP2H
  • Links
    NCBI Gene ID: 158401
    neXtProt AC: NX_Q5VXU9
    UniProt: Q5VXU9

  • Chr Location
    9q31.3; chr9:111686175-111795949 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    10 phenotypes from 2 alleles in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit embryonic lethality prior to E9.5. Male mice homozygous for a hypomorphic allele exhibit a lack of spermatozoa, reduced testis weight and size, increased male germ cell apoptosis, and abnormal male meiosis with defective chiasmata formation and chromosomal synapsis.
Gene Ontology
(GO)
Classifications
less
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000007630 VEGA Gene Model | MGI Sequence Detail 95231 C57BL/6J ±  kb
transcript OTTMUST00000017528 VEGA | MGI Sequence Detail 4664 Not Applicable  
polypeptide OTTMUSP00000008098 VEGA | MGI Sequence Detail 1481 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    432 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
Molecular
Reagents
less
  • All nucleic 8
    cDNA 8

    Microarray probesets 2
Other
Accession IDs
less
MGI:2685272
References
more
  • Summaries
    All 22
    Phenotypes 5
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:262079 Guiraldelli MF, et al., SHOC1 is a ERCC4-(HhH)2-like protein, integral to the formation of crossover recombination intermediates during mammalian meiosis. PLoS Genet. 2018 May;14(5):e1007381

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/10/2018
MGI 6.12
The Jackson Laboratory