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Camta1 Gene Detail
Summary
  • Symbol
    Camta1
  • Name
    calmodulin binding transcription activator 1
  • Synonyms
    1810059M14Rik, 2310058O09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2140230
    NCBI Gene: 100072
  • Gene Overview
    MyGene.info: CAMTA1
Location & Maps
more
  • Sequence Map
    Chr4:151059525-151861876 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      802352 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    CAMTA1, calmodulin binding transcription activator 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CAMTA1, calmodulin binding transcription activator 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CANPMR
  • Links
    NCBI Gene ID: 23261
    neXtProt AC: NX_Q9Y6Y1

  • Chr Location
    1p36.31-p36.23; chr1:6785324-7769706 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human CAMTA1 associations

Human Disease Mouse Models
       Cerebellar Ataxia, Nonprogressive, with Mental Retardation; CANPMR   OMIM: 614756
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    14 phenotypes from 2 alleles in 2 genetic backgrounds
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    36
  • Gene trapped
    30
  • Targeted
    6
  • Genomic Mutations
    3 involving Camta1
  • Incidental Mutations
Global or nervous system deletion of this gene results in decreased body size, severe ataxia, progressive Purkinje cell degeneration, and cerebellar atrophy.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000010309 VEGA Gene Model | MGI Sequence Detail 802352 C57BL/6J ±  kb
transcript OTTMUST00000024009 VEGA | MGI Sequence Detail 8423 Not Applicable  
polypeptide OTTMUSP00000011013 VEGA | MGI Sequence Detail 1682 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    6802 from dbSNP Build 142
Protein
Information
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Molecular
Reagents
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  • All nucleic 27
    Genomic 1
    cDNA 22
    Primer pair 4

    Microarray probesets 12
Other
Accession IDs
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MGI:1922837, MGI:1922929, MGI:2140626
References
more
  • Summaries
    All 38
    Developmental Gene Expression 5
    Gene Ontology 5
    Phenotypes 13
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
  • Latest
    J:212232 Long C, et al., Ataxia and Purkinje cell degeneration in mice lacking the CAMTA1 transcription factor. Proc Natl Acad Sci U S A. 2014 Aug 5;111(31):11521-6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
04/26/2016
MGI 6.03
The Jackson Laboratory