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Ints3 Gene Detail
Summary
  • Symbol
    Ints3
  • Name
    integrator complex subunit 3
  • Feature Type
    protein coding gene
  • IDs
    MGI:2140050
    NCBI Gene: 229543
  • Gene Overview
    MyGene.info: INTS3
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:90391388-90433622 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 39.22 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    172 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2140050
protein coding gene Chr3:90391380-90433636 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027463
protein coding gene Chr3:90700131-90743749 (-)
A/J MGP_AJ_G0027427
protein coding gene Chr3:87680603-87723447 (-)
AKR/J MGP_AKRJ_G0027392
protein coding gene Chr3:89837734-89881378 (-)
BALB/cJ MGP_BALBcJ_G0027436
protein coding gene Chr3:87636997-87679120 (-)
C3H/HeJ MGP_C3HHeJ_G0027178
protein coding gene Chr3:90000086-90043772 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027882
protein coding gene Chr3:94103445-94146527 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025235
protein coding gene Chr3:83174122-83216884 (-)
CAST/EiJ MGP_CASTEiJ_G0026624
protein coding gene Chr3:90383158-90430494 (-)
CBA/J MGP_CBAJ_G0027153
protein coding gene Chr3:97331797-97373889 (-)
DBA/2J MGP_DBA2J_G0027290
protein coding gene Chr3:87047748-87089767 (-)
FVB/NJ MGP_FVBNJ_G0027258
protein coding gene Chr3:85382067-85424195 (-)
LP/J MGP_LPJ_G0027399
protein coding gene Chr3:91764784-91808591 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027279
protein coding gene Chr3:103548377-103594522 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027941
protein coding gene Chr3:89579374-89625325 (-)
PWK/PhJ MGP_PWKPhJ_G0026358
protein coding gene Chr3:86939507-86983420 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026178
protein coding gene Chr3:88759517-88801113 (-)
WSB/EiJ MGP_WSBEiJ_G0026706
protein coding gene Chr3:89981624-90025523 (-)



Homology
more
  • Human Ortholog
    INTS3, integrator complex subunit 3
  • Vertebrate Orthologs
    8
  • Human Ortholog
    INTS3, integrator complex subunit 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C1orf193, C1orf60, INT3, SOSSA, SOSS-A
  • Links
    NCBI Gene ID: 65123
    neXtProt AC: NX_Q68E01
    UniProt: Q68E01

  • Chr Location
    1q21.3; chr1:153728050-153774808 (+)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000027933 Ensembl Gene Model | MGI Sequence Detail 42235 C57BL/6J ±  kb
transcript ENSMUST00000071488 Ensembl | MGI Sequence Detail 4038 Not Applicable  
polypeptide ENSMUSP00000071422 Ensembl | MGI Sequence Detail 1041 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 173
    cDNA 173

    Microarray probesets 4
References
more
  • Summaries
    All 29
    Diseases 1
    Gene Ontology 1
    Phenotypes 8
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory