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Cept1 Gene Detail
Summary
  • Symbol
    Cept1
  • Name
    choline/ethanolaminephosphotransferase 1
  • Synonyms
    9930118K05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2139793
    NCBI Gene: 99712
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr3:106502260-106547802 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      45543 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 46.49 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    CEPT1, choline/ethanolamine phosphotransferase 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CEPT1, choline/ethanolamine phosphotransferase 1
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 10390
    neXtProt AC: NX_Q9Y6K0
    UniProt: Q9Y6K0

  • Chr Location
    1p13.3; chr1:111139436-111185102 (+)  GRCh38.p7

Human Diseases
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  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    12 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Conditional homozygous knockout in skeletal muscle leads to improved glucose tolerance, increased insulin sensitivity and muscle weakness in mice fed a high fat diet.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic OTTMUSG00000029486 VEGA Gene Model | MGI Sequence Detail 45543 C57BL/6J ±  kb
    transcript OTTMUST00000073058 VEGA | MGI Sequence Detail 2814 Not Applicable  
    polypeptide OTTMUSP00000037777 VEGA | MGI Sequence Detail 416 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      157 from dbSNP Build 142
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 13
      cDNA 13

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:2140023
    References
    more
    • Summaries
      All 34
      Developmental Gene Expression 1
      Diseases 1
      Gene Ontology 5
      Phenotypes 11
    • Earliest
      J:70677 Cook SA, et al., Mouse paracentric inversion In(3)55Rk mutates the urate oxidase gene. Cytogenet Cell Genet. 2001;93(1-2):77-82
    • Latest
      J:249456 Funai K, et al., Skeletal Muscle Phospholipid Metabolism Regulates Insulin Sensitivity and Contractile Function. Diabetes. 2016 Feb;65(2):358-70

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    Funding Information
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    last database update
    05/15/2018
    MGI 6.12
    The Jackson Laboratory