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Clca4b Gene Detail
Summary
  • Symbol
    Clca4b
  • Name
    chloride channel accessory 4B
  • Synonyms
    AI747448
  • Feature Type
    protein coding gene
  • IDs
    MGI:2139790
    NCBI Gene: 99709
  • Gene Overview
    MyGene.info: CLCA4
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:144910921-144932529 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 69.20 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    178 from dbSNP Build 142
  • Strain Annotations
    12
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2139790
protein coding gene Chr3:144910921-144932529 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027955
protein coding gene Chr3:148228648-148249947 (-)
A/J MGP_AJ_G0027914
protein coding gene Chr3:143021613-143043611 (-)
AKR/J MGP_AKRJ_G0027880
protein coding gene Chr3:146803620-146830363 (-)
BALB/cJ MGP_BALBcJ_G0027926
protein coding gene Chr3:142823658-142861076 (-)
C3H/HeJ MGP_C3HHeJ_G0027656
protein coding gene Chr3:147170390-147194251 (-)
C57BL/6NJ no annotation
CAROLI/EiJ MGP_CAROLIEiJ_G0025707
protein coding gene Chr3:138032539-138057125 (-)
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J MGP_DBA2J_G0027771
protein coding gene Chr3:142173960-142199131 (-)
FVB/NJ MGP_FVBNJ_G0027737
protein coding gene Chr3:139582170-139608898 (-)
LP/J MGP_LPJ_G0027881
protein coding gene Chr3:149643692-149669874 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027770
protein coding gene Chr3:167043593-167108562 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028427
protein coding gene Chr3:146396197-146432182 (-)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    CLCA4, chloride channel accessory 4
  • Vertebrate Orthologs
    8
  • Human Ortholog
    CLCA4, chloride channel accessory 4
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CaCC, CaCC2
  • Links
    NCBI Gene ID: 22802
    neXtProt AC: NX_Q14CN2
    UniProt: Q14CN2

  • Chr Location
    1p22.3; chr1:86547076-86580758 (+)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    5 phenotype references
No notable phenotype was detected in a high throughput screen of homozyogus mutant null mice.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 99709 NCBI Gene Model | MGI Sequence Detail 21609 C57BL/6J ±  kb
transcript NM_001033199 RefSeq | MGI Sequence Detail 2997 C57BL/6  
polypeptide NP_001028371 RefSeq | MGI Sequence Detail 925 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR013642 Calcium-activated chloride channel, N-terminal
    IPR004727 Calcium-activated chloride channel protein, chordata
    IPR013783 Immunoglobulin-like fold
    IPR036465 von Willebrand factor A-like domain superfamily
    IPR002035 von Willebrand factor, type A
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 3
References
more
  • Summaries
    All 20
    Diseases 1
    Gene Ontology 2
    Phenotypes 5
  • Earliest
    J:70677 Cook SA, et al., Mouse paracentric inversion In(3)55Rk mutates the urate oxidase gene. Cytogenet Cell Genet. 2001;93(1-2):77-82
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory