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Clca4a Gene Detail
Summary
  • Symbol
    Clca4a
  • Name
    chloride channel accessory 4A
  • Synonyms
    9130020L07Rik, Clca6
  • Feature Type
    protein coding gene
  • IDs
    MGI:2139744
    NCBI Gene: 99663
  • Gene Overview
    MyGene.info: CLCA4
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:144952486-144975045 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 69.22 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    358 from dbSNP Build 142
  • Strain Annotations
    11
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2139744
protein coding gene Chr3:144952480-144975045 (-)
129S1/SvImJ no annotation
A/J MGP_AJ_G0027913
protein coding gene Chr3:142969869-143082405 (-)
AKR/J MGP_AKRJ_G0027879
protein coding gene Chr3:146742181-146879736 (-)
BALB/cJ MGP_BALBcJ_G0027925
protein coding gene Chr3:142760697-142896905 (-)
C3H/HeJ MGP_C3HHeJ_G0027655
protein coding gene Chr3:147119466-147246599 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028369
protein coding gene Chr3:153425632-153460647 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025708
protein coding gene Chr3:138032539-138057126 (-)
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J no annotation
FVB/NJ MGP_FVBNJ_G0027738
protein coding gene Chr3:139625988-139651237 (-)
LP/J MGP_LPJ_G0027882
protein coding gene Chr3:149685041-149706699 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027771
protein coding gene Chr3:167082935-167108563 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028428
protein coding gene Chr3:146446580-146472320 (-)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    CLCA4, chloride channel accessory 4
  • Vertebrate Orthologs
    8
  • Human Ortholog
    CLCA4, chloride channel accessory 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CaCC, CaCC2
  • Links
    NCBI Gene ID: 22802
    neXtProt AC: NX_Q14CN2
    UniProt: Q14CN2

  • Chr Location
    1p22.3; chr1:86547076-86580758 (+)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 99663 NCBI Gene Model | MGI Sequence Detail 22560 C57BL/6J ±  kb
transcript NM_207208 RefSeq | MGI Sequence Detail 2998 C57BL/6  
polypeptide Q6Q473 UniProt | EBI | MGI Sequence Detail 924 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • EC
  • InterPro Domains
    IPR013642 Calcium-activated chloride channel, N-terminal
    IPR004727 Calcium-activated chloride channel protein, chordata
    IPR013783 Immunoglobulin-like fold
    IPR036465 von Willebrand factor A-like domain superfamily
    IPR002035 von Willebrand factor, type A
Molecular
Reagents
less
  • All nucleic 8
    Genomic 1
    cDNA 6
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 4
    Phenotypes 3
  • Earliest
    J:70677 Cook SA, et al., Mouse paracentric inversion In(3)55Rk mutates the urate oxidase gene. Cytogenet Cell Genet. 2001;93(1-2):77-82
  • Latest
    J:187011 Rajagopal M, et al., Differential effects of extracellular ATP on chloride transport in cortical collecting duct cells. Am J Physiol Renal Physiol. 2012 Aug;303(4):F483-91

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory