Clca6
Gene Detail

Symbol Name ID

Clca6 chloride channel calcium activated 6 MGI:2139744

Synonyms

9130020L07Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 3

69.22 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr3:144952480-144975045 bp, - strand From VEGA annotation of GRCm38   22566 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:40808  Vertebrate Homology Class
1 human; 2 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Protein SuperFamily: calcium-activated chloride channel
Gene Tree: Clca6

Human homologs

Human Homolog		CLCA4, chloride channel accessory 4
NCBI Gene ID		22802
neXtProt AC		NX_Q14CN2
Human Synonyms		CaCC, CaCC2
Human Chr (Location)		1p31-p22; chr1:87012759-87046437 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(1) : Targeted(1)

Gene Ontology (GO) classifications

All GO classifications: (12 annotations)

Process	chloride transport, ion transmembrane transport, ...
Component	extracellular region, integral to membrane, ...
Function	chloride channel activity, ligand-gated ion channel activity

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (8)    Tissues (8)    Images (1)
Theiler Stages: 28

Assay Type	Results
RT-PCR	8

cDNA source data(6)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(9) cDNA(6) Primer pair(1) Other(2)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000031904 (Evidence)
Ensembl Gene Model	ENSMUSG00000068547 (Evidence)
Entrez Gene	99663 (Evidence)
UniGene	442050
DoTS	DT.102525938, DT.55187029
Consensus CDS Project	CCDS38661.1
International Mouse Knockout Project Status	Clca6

Sequences

Length	Strain/Species
genomic	OTTMUSG00000031904	VEGA Gene Model | MGI Sequence Detail	22566	C57BL/6J
transcript	OTTMUST00000079097	VEGA | MGI Sequence Detail	3004	Not Applicable
polypeptide	OTTMUSP00000042144	VEGA | MGI Sequence Detail	925	Not Applicable

All sequences(26) RefSeq(2) UniProt(3)

Polymorphisms

SNPs(215 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR004727	Calcium-activated chloride channel protein
InterPro	IPR013642	Chloride channel calcium-activated
InterPro	IPR015394	Domain of unknown function DUF1973
InterPro	IPR002035	von Willebrand factor, type A
Protein Ontology	PR:000005525	calcium-activated chloride channel regulator 4

References

(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:187011 Rajagopal M, et al., Differential effects of extracellular ATP on chloride transport in cortical collecting duct cells. Am J Physiol Renal Physiol. 2012 Aug;303(4):F483-91
All references(27)