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Clca4a Gene Detail
Summary
  • Symbol
    Clca4a
  • Name
    chloride channel accessory 4A
  • Synonyms
    9130020L07Rik, Clca6
  • Feature Type
    protein coding gene
  • IDs
    MGI:2139744
    NCBI Gene: 99663
  • Gene Overview
    MyGene.info: CLCA4
Location & Maps
more
  • Sequence Map
    Chr3:144952480-144975045 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      22566 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 69.22 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    CLCA4, chloride channel accessory 4
  • Vertebrate Orthologs
    8
  • Human Ortholog
    CLCA4, chloride channel accessory 4
    Orthology source: HomoloGene
  • Synonyms
    CaCC, CaCC2
  • Links
    NCBI Gene ID: 22802
    neXtProt AC: NX_Q14CN2

  • Chr Location
    1p22.3; chr1:86547076-86580758 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
  • All Mutations and Alleles
    2
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    1 involving Clca4a
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031904 VEGA Gene Model | MGI Sequence Detail 22566 C57BL/6J ±  kb
transcript OTTMUST00000079097 VEGA | MGI Sequence Detail 3004 Not Applicable  
polypeptide OTTMUSP00000042144 VEGA | MGI Sequence Detail 925 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    358 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000005525 calcium-activated chloride channel regulator 4
  • EC
  • InterPro Domains
    IPR013642 Calcium-activated chloride channel protein
    IPR004727 Calcium-activated chloride channel protein, chordata
    IPR002035 von Willebrand factor, type A
Molecular
Reagents
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  • All nucleic 9
    cDNA 6
    Primer pair 1
    Other 2

    Microarray probesets 4
References
more
  • Summaries
    All 30
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 3
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:187011 Rajagopal M, et al., Differential effects of extracellular ATP on chloride transport in cortical collecting duct cells. Am J Physiol Renal Physiol. 2012 Aug;303(4):F483-91

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory