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Clca6
Gene Detail
 Symbol
Name
ID
Clca6
chloride channel calcium activated 6
MGI:2139744
Synonyms 9130020L07Rik
Feature Type protein coding gene
Genetic Map
Chromosome 3
69.22 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr3:144952480-144975045 bp, - strand
From VEGA annotation of GRCm38

  22566 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:40808  Vertebrate Homology Class
1 human; 2 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Protein SuperFamily: calcium-activated chloride channel
Gene Tree: Clca6

Human
homologs
Human Homolog CLCA4, chloride channel accessory 4
NCBI Gene ID 22802
neXtProt AC  NX_Q14CN2
Human Synonyms  CaCC, CaCC2
Human Chr (Location)  1p31-p22; chr1:86547015-86580754 (+)  GRCh38
Alleles
and
phenotypes
All alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process chloride transmembrane transport, chloride transport, ...
Component extracellular region, extracellular vesicular exosome, ...
Function chloride channel activity, ligand-gated ion channel activity
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (8)    Tissues (8)    Images (1)
Theiler Stages: 28
Assay TypeResults
RT-PCR 8
cDNA source data(6)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(9) cDNA(6) Primer pair(1) Other(2)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000031904 (Evidence)
Ensembl Gene ModelENSMUSG00000068547 (Evidence)
Entrez Gene99663 (Evidence)
UniGene442050
DoTSDT.102525938, DT.55187029
Consensus CDS ProjectCCDS38661.1
International Mouse Knockout Project StatusClca6
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031904 VEGA Gene Model | MGI Sequence Detail 22566 C57BL/6J ±  kb
transcript OTTMUST00000079097 VEGA | MGI Sequence Detail 3004 Not Applicable 
polypeptide OTTMUSP00000042144 VEGA | MGI Sequence Detail 925 Not Applicable 

For the selected sequences
All sequences(26) RefSeq(2) UniProt(3)
Polymorphisms SNPs within 2kb(368 from dbSNP Build 137)    SNPs within 2kb including multiple locations(386)
Protein-related
information
ResourceIDDescription
InterPro IPR004727 Calcium-activated chloride channel protein
InterPro IPR013642 Chloride channel calcium-activated
InterPro IPR015394 Domain of unknown function DUF1973
InterPro IPR002035 von Willebrand factor, type A
Protein Ontology PR:000005525 calcium-activated chloride channel regulator 4
References (Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:187011 Rajagopal M, et al., Differential effects of extracellular ATP on chloride transport in cortical collecting duct cells. Am J Physiol Renal Physiol. 2012 Aug;303(4):F483-91
All references(28)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory