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Snph
Gene Detail
Symbol

Name
ID
Snph
syntaphilin
MGI:2139270
Synonyms
mKIAA0374
Feature Type
protein coding gene
Genetic Map
Chromosome 2
74.83 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr2:151590549-151632593 bp, - strand
From VEGA annotation of GRCm38

  42045 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8817  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

HCOP human homology predictions: SNPH
Gene Tree: Snph

Human
homologs
SNPH, syntaphilin
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 9751
neXtProt AC: NX_O15079

Human Synonyms: bA314N13.5

Human Chr (Location): 20p13; chr20:1266297-1309327 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Mice with disruptions in this gene are viable, fertile, and morphologically normal. However, they do display subtile deficiencies in coordination.
 
Interactions
Snph interacts with 293 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process negative regulation of endocytosis, vesicle fusion
Component cell junction, cytoplasm, ...
Function syntaxin-1 binding
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (9)    Tissues (2)    Images (6)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 9
cDNA source data(40)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(40) cDNA(40)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000014818 (Evidence)
Ensembl Gene Model ENSMUSG00000027457 (Evidence)
Entrez Gene 241727 (Evidence)
UniGene 39312
DFCI TC1597196, TC1625957, TC1597233, TC1609297
DoTS DT.99854411, DT.94237657, DT.55220681, DT.101263875
NIA Mouse Gene Index U023490
Consensus CDS Project CCDS16871.1, CCDS71161.1, CCDS71162.1
International Mouse Phenotyping Consortium Status Snph
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000014818 VEGA Gene Model | MGI Sequence Detail 42045 C57BL/6J ±  kb
transcript OTTMUST00000035176 VEGA | MGI Sequence Detail 4730 Not Applicable 
polypeptide OTTMUSP00000015703 VEGA | MGI Sequence Detail 528 Not Applicable 

For the selected sequences
All sequences(85) RefSeq(16) UniProt(3)
Polymorphisms
SNPs within 2kb(265 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR026196 Syntaphilin
Protein Ontology PR:000015330 syntaphilin
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:212170 Ohno N, et al., Mitochondrial immobilization mediated by syntaphilin facilitates survival of demyelinated axons. Proc Natl Acad Sci U S A. 2014 Jul 8;111(27):9953-8
All references(41)
Other
accession IDs
MGI:2139400, MGI:2139413

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory