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Snph
Gene Detail
Symbol

Name
ID
Snph
syntaphilin
MGI:2139270
Synonyms
mKIAA0374
Feature Type
protein coding gene
Genetic Map
Chromosome 2
74.83 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr2:151590549-151632593 bp, - strand
From VEGA annotation of GRCm38

  42045 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8817  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Snph

Human
homologs
Human Homolog SNPH, syntaphilin
NCBI Gene ID 9751
neXtProt AC  NX_O15079
Human Synonyms  bA314N13.5
Human Chr (Location)  20p13; chr20:1266304-1309327 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice with disruptions in this gene are viable, fertile, and morphologically normal. However, they do display subtile deficiencies in coordination.
 
Interactions
Snph interacts with 293 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process negative regulation of endocytosis, vesicle fusion
Component cell junction, cytoplasm, ...
Function syntaxin-1 binding
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (9)    Tissues (2)    Images (6)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 9
cDNA source data(40)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(40) cDNA(40)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000014818 (Evidence)
Ensembl Gene ModelENSMUSG00000027457 (Evidence)
Entrez Gene241727 (Evidence)
UniGene39312
DFCITC1597196, TC1609297, TC1597233, TC1625957
DoTSDT.99854411, DT.94237657, DT.101263875, DT.55220681
NIA Mouse Gene IndexU023490
Consensus CDS ProjectCCDS16871.1, CCDS71161.1, CCDS71162.1
International Mouse Knockout Project StatusSnph
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000014818 VEGA Gene Model | MGI Sequence Detail 42045 C57BL/6J ±  kb
transcript OTTMUST00000035176 VEGA | MGI Sequence Detail 4730 Not Applicable 
polypeptide OTTMUSP00000015703 VEGA | MGI Sequence Detail 528 Not Applicable 

For the selected sequences
All sequences(85) RefSeq(14) UniProt(5)
Polymorphisms
SNPs within 2kb(265 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR026196 Syntaphilin
Protein Ontology PR:000015330 syntaphilin
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:212170 Ohno N, et al., Mitochondrial immobilization mediated by syntaphilin facilitates survival of demyelinated axons. Proc Natl Acad Sci U S A. 2014 Jul 8;111(27):9953-8
All references(42)
Other
accession IDs
MGI:2139400, MGI:2139413

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory