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Sec16a Gene Detail
Summary
  • Symbol
    Sec16a
  • Name
    SEC16 homolog A, endoplasmic reticulum export factor
  • Synonyms
    C230052J16Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2139207
    NCBI Gene: 227648
  • Gene Overview
    MyGene.info: SEC16A
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:26409431-26445216 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 18.89 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    126 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2139207
protein coding gene Chr2:26409431-26446060 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025489
protein coding gene Chr2:24360382-24399671 (-)
A/J MGP_AJ_G0025466
protein coding gene Chr2:23426647-23462416 (-)
AKR/J MGP_AKRJ_G0025436
protein coding gene Chr2:24189745-24227219 (-)
BALB/cJ MGP_BALBcJ_G0025462
protein coding gene Chr2:23535639-23572155 (-)
C3H/HeJ MGP_C3HHeJ_G0025223
protein coding gene Chr2:24148574-24185344 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025906
protein coding gene Chr2:25143819-25182764 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023317
protein coding gene Chr2:22306970-22344193 (-)
CAST/EiJ MGP_CASTEiJ_G0024686
protein coding gene Chr2:24021949-24062037 (-)
CBA/J MGP_CBAJ_G0025201
protein coding gene Chr2:25996800-26037179 (-)
DBA/2J MGP_DBA2J_G0025334
protein coding gene Chr2:23248351-23283899 (-)
FVB/NJ MGP_FVBNJ_G0025296
protein coding gene Chr2:23000001-23036140 (-)
LP/J MGP_LPJ_G0025420
protein coding gene Chr2:24303644-24343188 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025327
protein coding gene Chr2:26146846-26185182 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025965
protein coding gene Chr2:24148169-24185304 (-)
PWK/PhJ MGP_PWKPhJ_G0024434
protein coding gene Chr2:23051955-23088910 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024234
protein coding gene Chr2:24280965-24318453 (-)
WSB/EiJ MGP_WSBEiJ_G0024755
protein coding gene Chr2:24254469-24291112 (-)



Homology
more
  • Human Ortholog
    SEC16A, SEC16 homolog A, endoplasmic reticulum export factor
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SEC16A, SEC16 homolog A, endoplasmic reticulum export factor
    Orthology source: HomoloGene, HGNC
  • Synonyms
    KIAA0310, p250, SEC16L
  • Links
    NCBI Gene ID: 9919
    neXtProt AC: NX_O15027
    UniProt: O15027

  • Chr Location
    9q34.3; chr9:136440096-136484552 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 10533
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: SEC16A
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000026924 Ensembl Gene Model | MGI Sequence Detail 35786 C57BL/6J ±  kb
transcript ENSMUST00000114082 Ensembl | MGI Sequence Detail 8797 Not Applicable  
polypeptide ENSMUSP00000109716 Ensembl | MGI Sequence Detail 2377 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    10 Sequences
  • InterPro Domains
    IPR024298 Ancestral coatomer element 1, Sec16/Sec31
    IPR024880 COPII coat assembly protein, Sec16
    IPR024340 Sec16, central conserved domain
Molecular
Reagents
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  • All nucleic 211
    cDNA 211

    Microarray probesets 4
Other
Accession IDs
less
MGI:2443275
References
more
  • Summaries
    All 30
    Gene Ontology 7
    Phenotypes 6
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:236793 Bruno J, et al., SEC16A is a RAB10 effector required for insulin-stimulated GLUT4 trafficking in adipocytes. J Cell Biol. 2016 Jul 4;214(1):61-76

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory