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Cep152
Gene Detail
Symbol

Name
ID
Cep152
centrosomal protein 152
MGI:2139083
Feature Type
protein coding gene
Genetic Map
Chromosome 2
61.76 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr2:125563088-125625113 bp, - strand
From VEGA annotation of GRCm38

  62026 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:37159  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: CEP152
Gene Tree: Cep152

Human
homologs
CEP152, centrosomal protein 152kDa
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 22995
neXtProt AC: NX_O94986

Human Synonyms: MCPH4, MCPH9, SCKL5

Human Chr (Location): 15q21.1; chr15:48662534-48811918 (-)  GRCh38.p2

Disease Associations: (2) Diseases Associated with Human CEP152

Mutations,
alleles, and
phenotypes
All mutations/alleles(13) : Gene trapped(10) Targeted(3)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Cep152 interacts with 134 markers (Mir15a, Mir15b, Mir16-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process cell projection organization, centriole replication, ...
Component centrosome, cytoplasm, ...
Function protein binding, protein kinase binding
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (77)    Tissues (17)    Images (21)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 75
RT-PCR 2
cDNA source data(8)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase cep152    NEW 
Molecular
reagents
All nucleic(9) cDNA(8) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000015347 (Evidence)
Ensembl Gene Model ENSMUSG00000068394 (Evidence)
Entrez Gene 99100 (Evidence)
DFCI TC1597685, TC1672229, TC1622167
DoTS DT.55119065, DT.40162255, DT.40154784, DT.102538670, DT.101720048
NIA Mouse Gene Index U040970
Consensus CDS Project CCDS38229.1
International Mouse Phenotyping Consortium Status Cep152
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015347 VEGA Gene Model | MGI Sequence Detail 62026 C57BL/6J ±  kb
transcript OTTMUST00000036373 VEGA | MGI Sequence Detail 5768 Not Applicable 
polypeptide OTTMUSP00000016351 VEGA | MGI Sequence Detail 1736 Not Applicable 

For the selected sequences
All sequences(40) RefSeq(14) UniProt(1)
Polymorphisms
SNPs within 2kb(555 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000005342 centrosomal protein of 152 kDa
References
(Earliest) J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
(Latest) J:208632 Bazzi H, et al., Acentriolar mitosis activates a p53-dependent apoptosis pathway in the mouse embryo. Proc Natl Acad Sci U S A. 2014 Apr 15;111(15):E1491-500
All references(37)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory