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Myl9
Gene Detail
Symbol

Name
ID
Myl9
myosin, light polypeptide 9, regulatory
MGI:2138915
Synonyms
MLC20, Mylc2c, RLC-C
Feature Type
protein coding gene
Genetic Map
Chromosome 2
77.77 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr2:156775420-156781658 bp, + strand
From VEGA annotation of GRCm38

  6239 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:21230  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: MYL9
Gene Tree: Myl9

Human
homologs
MYL9, myosin, light chain 9, regulatory
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 10398
neXtProt AC: NX_P24844

Human Synonyms: LC20, MLC2, MLC-2C, MRLC1, MYRL2

Human Chr (Location): 20q11.23; chr20:36541484-36549823 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Interactions
Myl9 interacts with 52 markers (Mir30b, Mir30c-1, Mir30c-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process platelet aggregation
Component myosin complex, myosin II complex, ...
Function calcium ion binding, metal ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (14 records)
Data Summary: Results (346)    Tissues (176)    Images (38)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 338
Western blot 8
cDNA source data(170)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase myl9 ; ZFIN myl9a, myl9b    NEW 
Molecular
reagents
All nucleic(170) cDNA(170)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000016035 (Evidence)
Ensembl Gene Model ENSMUSG00000067818 (Evidence)
Entrez Gene 98932 (Evidence)
UniGene 271770
DFCI TC1572833
DoTS DT.55107496, DT.101740814
NIA Mouse Gene Index U002729
Consensus CDS Project CCDS50779.1
International Mouse Phenotyping Consortium Status Myl9
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016035 VEGA Gene Model | MGI Sequence Detail 6239 C57BL/6J ±  kb
transcript OTTMUST00000038239 VEGA | MGI Sequence Detail 1128 Not Applicable 
polypeptide OTTMUSP00000017149 VEGA | MGI Sequence Detail 172 Not Applicable 

For the selected sequences
All sequences(33) RefSeq(5) UniProt(1)
Polymorphisms
SNPs within 2kb(110 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR018247 EF-Hand 1, calcium-binding site
InterPro IPR002048 EF-hand domain
InterPro IPR011992 EF-hand-like domain
Protein Ontology PR:000010841 myosin regulatory light polypeptide 9
References
(Earliest) J:18786 Kubalak SW, et al., Chamber specification of atrial myosin light chain-2 expression precedes septation during murine cardiogenesis. J Biol Chem. 1994 Jun 17;269(24):16961-70
(Latest) J:220469 Grego-Bessa J, et al., Morphogenesis of the mouse neural plate depends on distinct roles of cofilin 1 in apical and basal epithelial domains. Development. 2015 Apr 1;142(7):1305-14
All references(47)
Other
accession IDs
MGD-MRK-36061, MGI:107493

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/20/2015
MGI 5.22
The Jackson Laboratory