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Slc5a12 Gene Detail
Summary
  • Symbol
    Slc5a12
  • Name
    solute carrier family 5 (sodium/glucose cotransporter), member 12
  • Synonyms
    SMCT2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2138890
    NCBI Gene: 241612
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:110597298-110647779 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 56.75 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    433 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2138890
protein coding gene Chr2:110597298-110649346 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026246
protein coding gene Chr2:112941607-112998045 (+)
A/J MGP_AJ_G0026207
protein coding gene Chr2:108221392-108285532 (+)
AKR/J MGP_AKRJ_G0026187
protein coding gene Chr2:111270093-111326277 (+)
BALB/cJ MGP_BALBcJ_G0026217
protein coding gene Chr2:108524808-108582680 (+)
C3H/HeJ MGP_C3HHeJ_G0025966
protein coding gene Chr2:111554598-111605484 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026668
protein coding gene Chr2:116630239-116687681 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024053
protein coding gene Chr2:103722721-103771806 (+)
CAST/EiJ MGP_CASTEiJ_G0025431
protein coding gene Chr2:112028526-112094064 (+)
CBA/J MGP_CBAJ_G0025944
protein coding gene Chr2:120622509-120692907 (+)
DBA/2J MGP_DBA2J_G0026082
protein coding gene Chr2:107729982-107780400 (+)
FVB/NJ MGP_FVBNJ_G0026045
protein coding gene Chr2:106644654-106698022 (+)
LP/J MGP_LPJ_G0026185
protein coding gene Chr2:113127870-113191375 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026069
protein coding gene Chr2:124821028-124884645 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026721
protein coding gene Chr2:111428588-111488735 (+)
PWK/PhJ MGP_PWKPhJ_G0025166
protein coding gene Chr2:107340612-107392221 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024966
protein coding gene Chr2:110670273-110733467 (+)
WSB/EiJ MGP_WSBEiJ_G0025498
protein coding gene Chr2:112177514-112238190 (+)



Homology
more
  • Human Ortholog
    SLC5A12, solute carrier family 5 member 12
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SLC5A12, solute carrier family 5 member 12
    Orthology source: HomoloGene, HGNC
  • Synonyms
    SMCT2
  • Links
    NCBI Gene ID: 159963
    neXtProt AC: NX_Q1EHB4
    UniProt: Q1EHB4

  • Chr Location
    11p14.2; chr11:26667019-26723356 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000041644 Ensembl Gene Model | MGI Sequence Detail 50482 C57BL/6J ±  kb
transcript ENSMUST00000045972 Ensembl | MGI Sequence Detail 3529 Not Applicable  
polypeptide ENSMUSP00000047340 Ensembl | MGI Sequence Detail 623 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 11
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 35
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 7
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:201479 Srivastava U, et al., Differences in health status affect susceptibility and mapping of genetic loci for atherosclerosis (fatty streak) in inbred mice. Arterioscler Thromb Vasc Biol. 2012 Oct;32(10):2380-6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
08/06/2019
MGI 6.14
The Jackson Laboratory