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Serpinb10
Gene Detail
 Symbol
Name
ID
Serpinb10
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 10
MGI:2138648
BioType Conflict
Feature Type protein coding gene
Genetic Map
Chromosome 1
50.34 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr1:107529003-107549271 bp, + strand
From VEGA annotation of GRCm38

  20269 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:68430  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 2 chicken

Protein SuperFamily: serpin

Human
homologs
Human Homolog SERPINB10, serpin peptidase inhibitor, clade B (ovalbumin), member 10
NCBI Gene ID 5273
neXtProt AC  NX_P48595
Human Synonyms  PI10, PI-10
Human Chr (Location)  18q21.3; chr18:63915511-63935242 (+)  GRCh38
Mutations,
alleles, and
phenotypes
Incidental mutations (data from Mutagenetix , APF )
Interactions
Serpinb10 interacts with 50 markers (Mir18b, Mir30a, Mir30b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process negative regulation of endopeptidase activity, negative regulation of peptidase activity, ...
Component cytoplasm, extracellular space, ...
Function peptidase inhibitor activity, serine-type endopeptidase inhibitor activity
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (139)    Tissues (6)    Images (48)
Theiler Stages: 23
Assay TypeResults
RNA in situ 139
cDNA source data(8)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(10) Genomic(2) cDNA(8)
Microarray probesets(1)
Other database
links
VEGA Gene ModelOTTMUSG00000020993 (Evidence)
Ensembl Gene ModelENSMUSG00000098034 (Evidence), ENSMUSG00000092572 (Evidence)
Entrez Gene241197 (Evidence)
UniGene123919
DFCITC1587895, TC1614389
DoTSDT.101725363, DT.91595852
NIA Mouse Gene IndexU000689
Consensus CDS ProjectCCDS48338.1
International Mouse Knockout Project StatusSerpinb10
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000020993 VEGA Gene Model | MGI Sequence Detail 20269 C57BL/6J ±  kb
transcript OTTMUST00000118497 VEGA | MGI Sequence Detail 1265 Not Applicable 
polypeptide OTTMUSP00000066138 VEGA | MGI Sequence Detail 320 Not Applicable 

For the selected sequences
All sequences(36) RefSeq(10) UniProt(2)
Polymorphisms SNPs within 2kb(98 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR023795 Protease inhibitor I4, serpin, conserved site
InterPro IPR023796 Serpin domain
InterPro IPR000215 Serpin family
Protein Ontology PR:000014690 serpin B10
References (Earliest) J:90640 Askew DJ, et al., Comparative genomic analysis of the clade B serpin cluster at human chromosome 18q21: amplification within the mouse squamous cell carcinoma antigen gene locus. Genomics. 2004 Jul;84(1):176-84
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(24)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory