Serpinb10
Gene Detail

Symbol Name ID

Serpinb10 serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 10 MGI:2138648

BioType Conflict

Feature Type

protein coding gene

Genetic Map

Chromosome 1

50.34 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr1:107529027-107549271 bp, + strand From VEGA annotation of GRCm38   20245 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:68430  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Protein SuperFamily: serpin
Gene Tree: Serpinb10

Human homologs

Human Homolog		SERPINB10, serpin peptidase inhibitor, clade B (ovalbumin), member 10
NCBI Gene ID		5273
neXtProt AC		NX_P48595
Human Synonyms		PI10, PI-10
Human Chr (Location)		18q21.3; chr18:61582745-61602476 (+)  GRCh37.p10

Gene Ontology (GO) classifications

All GO classifications: (8 annotations)

Process	negative regulation of endopeptidase activity, negative regulation of peptidase activity, ...
Component	cytoplasm, nucleus
Function	peptidase inhibitor activity, serine-type endopeptidase inhibitor activity

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (139)    Tissues (6)    Images (48)
Theiler Stages: 23

Assay Type	Results
RNA in situ	139

cDNA source data(8)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(10) Genomic(2) cDNA(8)
Microarray probesets(1)

Other database links

VEGA Gene Model	OTTMUSG00000020993 (Evidence)
Ensembl Gene Model	ENSMUSG00000092572 (Evidence)
Entrez Gene	241197 (Evidence)
UniGene	123919
DFCI	TC1587895, TC1614389
DoTS	DT.101725363, DT.91595852
NIA Mouse Gene Index	U000689
Consensus CDS Project	CCDS48338.1
International Mouse Knockout Project Status	Serpinb10

Sequences

Length	Strain/Species
genomic	OTTMUSG00000020993	VEGA Gene Model | MGI Sequence Detail	20245	C57BL/6J
transcript	OTTMUST00000049635	VEGA | MGI Sequence Detail	1194	Not Applicable
polypeptide	OTTMUSP00000043749	VEGA | MGI Sequence Detail	397	Not Applicable

All sequences(27) RefSeq(4) UniProt(2)

Polymorphisms

SNPs(35 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR023795	Protease inhibitor I4, serpin, conserved site
InterPro	IPR023796	Serpin domain
InterPro	IPR000215	Serpin family
Protein Ontology	PR:000014690	serpin B10

References

(Earliest) J:90640 Askew DJ, et al., Comparative genomic analysis of the clade B serpin cluster at human chromosome 18q21: amplification within the mouse squamous cell carcinoma antigen gene locus. Genomics. 2004 Jul;84(1):176-84
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(23)