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Atg9a
Gene Detail
Symbol

Name
ID
Atg9a
autophagy related 9A
MGI:2138446
Synonyms
Apg9l1
Feature Type
protein coding gene
Genetic Map
Chromosome 1
38.62 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr1:75180860-75192196 bp, - strand
From VEGA annotation of GRCm38

  11337 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:34495  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: ATG9A
Gene Tree: Atg9a

Human
homologs
ATG9A, autophagy related 9A
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 79065
neXtProt AC: NX_Q7Z3C6

Human Synonyms: APG9L1, mATG9, MGD3208

Human Chr (Location): 2q35; chr2:219219380-219229688 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Radiation induced(1) Spontaneous(1) Targeted(4)
Genomic Mutations involving Atg9a (2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Mice homozygous for a null mutation all die within 1 day of birth and display impaired autophagy.
 
Mutations Annotated to Human Diseases (1)   
Interactions
Atg9a interacts with 229 markers (Mir15a, Mir15b, Mir16-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (29 annotations)
Process autophagosome assembly, autophagy, ...
Component autophagosome, cytoplasm, ...
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(43)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase atg9a    NEW 
Molecular
reagents
All nucleic(43) cDNA(43)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000048480 (Evidence)
Ensembl Gene Model ENSMUSG00000033124 (Evidence)
Entrez Gene 245860 (Evidence)
UniGene 491221
DFCI TC1656355, TC1601368, TC1596242, TC1579947
NIA Mouse Gene Index U021493
Consensus CDS Project CCDS35622.1
International Mouse Phenotyping Consortium Status Atg9a
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000048480 VEGA Gene Model | MGI Sequence Detail 11337 C57BL/6J ±  kb
transcript OTTMUST00000124247 VEGA | MGI Sequence Detail 4218 Not Applicable 
polypeptide OTTMUSP00000067641 VEGA | MGI Sequence Detail 847 Not Applicable 

For the selected sequences
All sequences(78) RefSeq(15) UniProt(8)
Polymorphisms
SNPs within 2kb(47 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007241 Autophagy-related protein 9
Protein Ontology PR:000004420 autophagy-related protein 9A
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:209979 Mitzel DN, et al., Age-enhanced endoplasmic reticulum stress contributes to increased Atg9A inhibition of STING-mediated IFN-beta production during Streptococcus pneumoniae infection. J Immunol. 2014 May 1;192(9):4273-83
All references(38)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory