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Gtf3c3 Gene Detail
Summary
  • Symbol
    Gtf3c3
  • Name
    general transcription factor IIIC, polypeptide 3
  • Feature Type
    protein coding gene
  • IDs
    MGI:2138383
    NCBI Gene: 98488
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:54396004-54438971 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 27.13 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    232 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2138383
protein coding gene Chr1:54395877-54439026 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016025
protein coding gene Chr1:54065703-54105787 (-)
A/J MGP_AJ_G0016008
protein coding gene Chr1:52193841-52234153 (-)
AKR/J MGP_AKRJ_G0015964
protein coding gene Chr1:53590881-53629873 (-)
BALB/cJ MGP_BALBcJ_G0015963
protein coding gene Chr1:52245025-52288344 (-)
C3H/HeJ MGP_C3HHeJ_G0015795
protein coding gene Chr1:53851846-53888979 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016416
protein coding gene Chr1:56316654-56355250 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014138
protein coding gene Chr1:48297009-48338649 (-)
CAST/EiJ MGP_CASTEiJ_G0015377
protein coding gene Chr1:53117109-53156149 (-)
CBA/J MGP_CBAJ_G0015767
protein coding gene Chr1:57887452-57927125 (-)
DBA/2J MGP_DBA2J_G0015868
protein coding gene Chr1:51631462-51666675 (-)
FVB/NJ MGP_FVBNJ_G0015870
protein coding gene Chr1:50979278-51023074 (-)
LP/J MGP_LPJ_G0015940
protein coding gene Chr1:54902014-54939900 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0015890
protein coding gene Chr1:61020723-61080225 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016463
protein coding gene Chr1:53565006-53604734 (-)
PWK/PhJ MGP_PWKPhJ_G0015163
protein coding gene Chr1:50979133-51016651 (-)
SPRET/EiJ MGP_SPRETEiJ_G0014944
protein coding gene Chr1:53151538-53196489 (-)
WSB/EiJ MGP_WSBEiJ_G0015440
protein coding gene Chr1:53246865-53284602 (-)



Homology
more
  • Human Ortholog
    GTF3C3, general transcription factor IIIC subunit 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    GTF3C3, general transcription factor IIIC subunit 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    TFIIIC102, TFiiiC2-102, TFIIICgamma
  • Links
    NCBI Gene ID: 9330
    neXtProt AC: NX_Q9Y5Q9
    UniProt: Q9Y5Q9

  • Chr Location
    2q33.1; chr2:196763032-196799768 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 40805
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: GTF3C3
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000041303 Ensembl Gene Model | MGI Sequence Detail 42968 C57BL/6J ±  kb
transcript ENSMUST00000041638 Ensembl | MGI Sequence Detail 4582 Not Applicable  
polypeptide ENSMUSP00000039420 Ensembl | MGI Sequence Detail 882 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR011990 Tetratricopeptide-like helical domain superfamily
    IPR019734 Tetratricopeptide repeat
    IPR013026 Tetratricopeptide repeat-containing domain
    IPR039340 Transcription factor Tfc4/TFIIIC-102/Sfc4
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 2
References
more
  • Summaries
    All 25
    Developmental Gene Expression 3
    Gene Ontology 2
    Phenotypes 8
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:214809 Moniot B, et al., Prostaglandin D2 acts through the Dp2 receptor to influence male germ cell differentiation in the foetal mouse testis. Development. 2014 Sep;141(18):3561-71

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
06/04/2019
MGI 6.14
The Jackson Laboratory