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Tmem237
Gene Detail
Symbol

Name
ID
Tmem237
transmembrane protein 237
MGI:2138365
Synonyms
Als2cr4, LOC381259
Feature Type
protein coding gene
Genetic Map
Chromosome 1
29.20 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr1:59100590-59120408 bp, - strand
From VEGA annotation of GRCm38

  19819 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:17570  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

HCOP human homology predictions: TMEM237
Gene Tree: Tmem237

Human
homologs
TMEM237, transmembrane protein 237
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 65062
neXtProt AC: NX_Q96Q45

Human Synonyms: ALS2CR4, JBTS14

Human Chr (Location): chr2:201620184-201643529 (-)  GRCh38.p2

Disease Associations: (2) Diseases Associated with Human TMEM237

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Gene trapped(2) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Tmem237 interacts with 104 markers (Mir7-1, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process cell projection organization, cilium assembly, ...
Component cell projection, ciliary transition zone, ...
Function molecular_function
External Resources: FuncBase
Expression
cDNA source data(34)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase tmem237    NEW 
Molecular
reagents
All nucleic(34) cDNA(34)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000047221 (Evidence)
Ensembl Gene Model ENSMUSG00000038079 (Evidence)
Entrez Gene 381259 (Evidence)
UniGene 261275
DFCI TC1580203
DoTS DT.50316719, DT.99844693, DT.99844694
NIA Mouse Gene Index U021366
Consensus CDS Project CCDS14983.1, CCDS14984.1
International Mouse Phenotyping Consortium Status Tmem237
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000047221 VEGA Gene Model | MGI Sequence Detail 19819 C57BL/6J ±  kb
transcript OTTMUST00000122102 VEGA | MGI Sequence Detail 1533 Not Applicable 
polypeptide OTTMUSP00000067075 VEGA | MGI Sequence Detail 427 Not Applicable 

For the selected sequences
All sequences(53) RefSeq(8) UniProt(3)
Polymorphisms
SNPs within 2kb(135 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000003976 transmembrane protein 237
References
(Earliest) J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
(Latest) J:182461 Huang L, et al., TMEM237 is mutated in individuals with a Joubert syndrome related disorder and expands the role of the TMEM family at the ciliary transition zone. Am J Hum Genet. 2011 Dec 9;89(6):713-30
All references(30)
Other
accession IDs
MGI:2685818

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory