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Tmem237
Gene Detail
 Symbol
Name
ID
Tmem237
transmembrane protein 237
MGI:2138365
Synonyms Als2cr4, LOC381259
Feature Type protein coding gene
Genetic Map
Chromosome 1
29.20 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr1:59100594-59120096 bp, - strand
From Ensembl annotation of GRCm38

  19503 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:17570  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 zebrafish

Gene Tree: Tmem237

Human
homologs
Human Homolog TMEM237, transmembrane protein 237
NCBI Gene ID 65062
neXtProt AC  NX_Q96Q45
Human Synonyms  ALS2CR4, JBTS14
Human Chr (Location)  chr2:201620184-201643529 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human TMEM237
Alleles
and
phenotypes
All alleles(4) : Targeted(2) Gene trapped(2)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process cell projection organization, cilium assembly, ...
Component cell projection, ciliary transition zone, ...
Function molecular_function
External Resources: FuncBase
Expression
cDNA source data(34)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(34) cDNA(34)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000038079 (Evidence)
Entrez Gene381259 (Evidence)
UniGene261275
DFCITC1580203
DoTSDT.50316719, DT.99844693, DT.99844694
NIA Mouse Gene IndexU021366
Consensus CDS ProjectCCDS14983.1, CCDS14984.1
International Mouse Knockout Project StatusTmem237
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000038079 Ensembl Gene Model | MGI Sequence Detail 19503 C57BL/6J ±  kb
transcript ENSMUST00000094917 Ensembl | MGI Sequence Detail 1867 Not Applicable 
polypeptide ENSMUSP00000092522 Ensembl | MGI Sequence Detail 413 Not Applicable 

For the selected sequences
All sequences(30) RefSeq(8) UniProt(1)
Polymorphisms SNPs within 2kb(134 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000003976 amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein
References (Earliest) J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
(Latest) J:182461 Huang L, et al., TMEM237 is mutated in individuals with a Joubert syndrome related disorder and expands the role of the TMEM family at the ciliary transition zone. Am J Hum Genet. 2011 Dec 9;89(6):713-30
All references(31)
Other
accession IDs
MGI:2685818

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory