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Tmem237 Gene Detail
Summary
  • Symbol
    Tmem237
  • Name
    transmembrane protein 237
  • Synonyms
    Als2cr4, LOC381259
  • Feature Type
    protein coding gene
  • IDs
    MGI:2138365
    NCBI Gene: 381259
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:59100590-59120408 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 29.20 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    131 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2138365
protein coding gene Chr1:59100584-59120695 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016062
protein coding gene Chr1:59050432-59068669 (-)
A/J MGP_AJ_G0016045
protein coding gene Chr1:56995293-57014321 (-)
AKR/J MGP_AKRJ_G0016001
protein coding gene Chr1:58590090-58611147 (-)
BALB/cJ MGP_BALBcJ_G0016000
protein coding gene Chr1:57037553-57057133 (-)
C3H/HeJ MGP_C3HHeJ_G0015832
protein coding gene Chr1:58839401-58858048 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016453
protein coding gene Chr1:61373877-61402578 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014174
protein coding gene Chr1:52821582-52838267 (-)
CAST/EiJ MGP_CASTEiJ_G0015414
protein coding gene Chr1:57977925-57995968 (-)
CBA/J MGP_CBAJ_G0015804
protein coding gene Chr1:63295842-63317685 (-)
DBA/2J MGP_DBA2J_G0015905
protein coding gene Chr1:56420528-56439476 (-)
FVB/NJ MGP_FVBNJ_G0015907
protein coding gene Chr1:55723736-55743069 (-)
LP/J MGP_LPJ_G0015977
protein coding gene Chr1:59931643-59949825 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0015927
protein coding gene Chr1:66234682-66255785 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016500
protein coding gene Chr1:58499979-58520289 (-)
PWK/PhJ MGP_PWKPhJ_G0015201
protein coding gene Chr1:55760461-55780093 (-)
SPRET/EiJ MGP_SPRETEiJ_G0014981
protein coding gene Chr1:58027411-58045415 (-)
WSB/EiJ MGP_WSBEiJ_G0015477
protein coding gene Chr1:58204131-58223463 (-)



Homology
more
  • Human Ortholog
    TMEM237, transmembrane protein 237
  • Vertebrate Orthologs
    11
  • Human Ortholog
    TMEM237, transmembrane protein 237
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ALS2CR4, JBTS14
  • Links
    NCBI Gene ID: 65062
    neXtProt AC: NX_Q96Q45
    UniProt: Q96Q45

  • Chr Location
    chr2:201620184-201643529 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human TMEM237 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000038079 Ensembl Gene Model | MGI Sequence Detail 19819 C57BL/6J ±  kb
transcript ENSMUST00000186794 Ensembl | MGI Sequence Detail 1533 Not Applicable  
polypeptide ENSMUSP00000139823 Ensembl | MGI Sequence Detail 427 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 36
    cDNA 36

    Microarray probesets 3
Other
Accession IDs
less
MGI:2685818
References
more
  • Summaries
    All 34
    Gene Ontology 3
    Phenotypes 9
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:182461 Huang L, et al., TMEM237 is mutated in individuals with a Joubert syndrome related disorder and expands the role of the TMEM family at the ciliary transition zone. Am J Hum Genet. 2011 Dec 9;89(6):713-30

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
08/06/2019
MGI 6.14
The Jackson Laboratory