Tmem237
Gene Detail

Symbol Name ID

Tmem237 transmembrane protein 237 MGI:2138365

Synonyms

Als2cr4, LOC381259

Feature Type

protein coding gene

Genetic Map

Chromosome 1

29.20 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr1:59100594-59120096 bp, - strand From Ensembl annotation of GRCm38   19503 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:17570  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 zebrafish

Gene Tree: Tmem237

Human homologs

Human Homolog		TMEM237, transmembrane protein 237
NCBI Gene ID		65062
neXtProt AC		NX_Q96Q45
Human Synonyms		ALS2CR4, JBTS14
Human Chr (Location)		chr2:202484907-202508252 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human TMEM237

Alleles and phenotypes

All alleles(4) : Targeted(2) Gene trapped(2)

Gene Ontology (GO) classifications

All GO classifications: (12 annotations)

Process	cell projection organization, cilium assembly, ...
Component	cell projection, ciliary transition zone, ...
Function	molecular_function

External Resources: FuncBase

Expression

cDNA source data(34)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(34) cDNA(34)
Microarray probesets(3)

Other database links

Ensembl Gene Model	ENSMUSG00000038079 (Evidence)
Entrez Gene	381259 (Evidence)
UniGene	261275
DFCI	TC1580203
DoTS	DT.50316719, DT.99844693, DT.99844694
NIA Mouse Gene Index	U021366
Consensus CDS Project	CCDS14983.1, CCDS14984.1
International Mouse Knockout Project Status	Tmem237

Sequences

Length	Strain/Species
genomic	ENSMUSG00000038079	Ensembl Gene Model | MGI Sequence Detail	19503	C57BL/6J
transcript	ENSMUST00000094917	Ensembl | MGI Sequence Detail	1867	Not Applicable
polypeptide	ENSMUSP00000092522	Ensembl | MGI Sequence Detail	413	Not Applicable

All sequences(26) RefSeq(4) UniProt(1)

Polymorphisms

SNPs(100 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
Protein Ontology	PR:000003976	amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein

References

(Earliest) J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
(Latest) J:182461 Huang L, et al., TMEM237 is mutated in individuals with a Joubert syndrome related disorder and expands the role of the TMEM family at the ciliary transition zone. Am J Hum Genet. 2011 Dec 9;89(6):713-30
All references(31)

Other accession IDs

MGI:2685818