About   Help   FAQ
Ifi207 Gene Detail
Summary
  • Symbol
    Ifi207
  • Name
    interferon activated gene 207
  • Synonyms
    AI607873, Pyhin-A
  • Feature Type
    protein coding gene
  • IDs
    MGI:2138302
    NCBI Gene: 226691
  • Gene Overview
    MyGene.info: IFI16
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:173723427-173741747 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 80.61 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    21 from dbSNP Build 142
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2138302
protein coding gene Chr1:173723424-173741831 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016813
protein coding gene Chr1:179683663-179703527 (-)
A/J MGP_AJ_G0016791
protein coding gene Chr1:172431511-172449865 (-)
AKR/J MGP_AKRJ_G0016758
protein coding gene Chr1:177606581-177629807 (-)
BALB/cJ MGP_BALBcJ_G0016751
protein coding gene Chr1:172941467-172960246 (-)
C3H/HeJ MGP_C3HHeJ_G0016575
protein coding gene Chr1:178234006-178252508 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017213
protein coding gene Chr1:185706567-185724540 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014921
protein coding gene Chr1:164100843-164117649 (-)
CAST/EiJ MGP_CASTEiJ_G0016157
protein coding gene Chr1:177531910-177549723 (-)
CBA/J MGP_CBAJ_G0016550
protein coding gene Chr1:192460841-192480441 (-)
DBA/2J MGP_DBA2J_G0016656
protein coding gene Chr1:171367377-171386448 (-)
FVB/NJ MGP_FVBNJ_G0016651
protein coding gene Chr1:169475958-169494318 (-)
LP/J MGP_LPJ_G0016729
protein coding gene Chr1:180766714-180784765 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016681
protein coding gene Chr1:199561940-199587569 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017250
protein coding gene Chr1:177456809-177475870 (-)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0016217
protein coding gene Chr1:177547580-177556813 (-)



Homology
more
  • Human Ortholog
    IFI16, interferon gamma inducible protein 16
  • Vertebrate Orthologs
    16
  • Human Ortholog
    IFI16, interferon gamma inducible protein 16
    Orthology source: HomoloGene
  • Synonyms
    IFNGIP1, PYHIN2
  • Links
    NCBI Gene ID: 3428
    neXtProt AC: NX_Q16666
    UniProt: Q16666

  • Chr Location
    1q23.1; chr1:158999968-159055155 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000073490 Ensembl Gene Model | MGI Sequence Detail 18321 C57BL/6J ±  kb
transcript ENSMUST00000042610 Ensembl | MGI Sequence Detail 3422 Not Applicable  
polypeptide ENSMUSP00000048129 Ensembl | MGI Sequence Detail 978 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    cDNA 8

    Microarray probesets 2
References
more
  • Summaries
    All 20
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:10055 Choubey D, et al., Interferons as gene activators. Indications for repeated gene duplication during the evolution of a cluster of interferon-activatable genes on murine chromosome 1. J Biol Chem. 1989 Oct 15;264(29):17182-9
  • Latest
    J:234263 Gray EE, et al., The AIM2-like Receptors Are Dispensable for the Interferon Response to Intracellular DNA. Immunity. 2016 Aug 16;45(2):255-66

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/03/2019
MGI 6.14
The Jackson Laboratory