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Sh3bp4 Gene Detail
Summary
  • Symbol
    Sh3bp4
  • Name
    SH3-domain binding protein 4
  • Synonyms
    BOG25
  • Feature Type
    protein coding gene
  • IDs
    MGI:2138297
    NCBI Gene: 98402
  • Gene Overview
    MyGene.info: SH3BP4
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:89070462-89155068 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 45.05 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    675 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2138297
protein coding gene Chr1:89070415-89155068 (.)
129S1/SvImJ MGP_129S1SvImJ_G0016289
protein coding gene Chr1:90520717-90601424 (+)
A/J MGP_AJ_G0016270
protein coding gene Chr1:87269155-87348105 (+)
AKR/J MGP_AKRJ_G0016231
protein coding gene Chr1:89850191-89931549 (+)
BALB/cJ MGP_BALBcJ_G0016226
protein coding gene Chr1:87412431-87492715 (+)
C3H/HeJ MGP_C3HHeJ_G0016055
protein coding gene Chr1:90065209-90146092 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016685
protein coding gene Chr1:94035765-94122648 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014403
protein coding gene Chr1:81562368-81643107 (+)
CAST/EiJ MGP_CASTEiJ_G0015640
protein coding gene Chr1:89378098-89463614 (+)
CBA/J MGP_CBAJ_G0016031
protein coding gene Chr1:97021195-97103213 (+)
DBA/2J MGP_DBA2J_G0016134
protein coding gene Chr1:86492317-86572180 (+)
FVB/NJ no annotation
LP/J MGP_LPJ_G0016205
protein coding gene Chr1:91660032-91741119 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016158
protein coding gene Chr1:100359074-100438499 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016725
protein coding gene Chr1:89877914-89956810 (+)
PWK/PhJ MGP_PWKPhJ_G0015424
protein coding gene Chr1:85889873-85970100 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015207
protein coding gene Chr1:88766485-88850150 (+)
WSB/EiJ MGP_WSBEiJ_G0015698
protein coding gene Chr1:89592664-89673026 (+)



Homology
more
  • Human Ortholog
    SH3BP4, SH3 domain binding protein 4
  • Vertebrate Orthologs
    11
  • Human Ortholog
    SH3BP4, SH3 domain binding protein 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BOG25, TTP
  • Links
    NCBI Gene ID: 23677
    neXtProt AC: NX_Q9P0V3
    UniProt: Q9P0V3

  • Chr Location
    2q37.2; chr2:234951984-235055714 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 8726
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;2 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: SH3BP4
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    15 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 98402 NCBI Gene Model | MGI Sequence Detail 84607 C57BL/6J ±  kb
transcript NM_133816 RefSeq | MGI Sequence Detail 5014 C57BL/6  
polypeptide Q921I6 UniProt | EBI | MGI Sequence Detail 962 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    cDNA 13

    Microarray probesets 5
Other
Accession IDs
less
MGI:2138581
References
more
  • Summaries
    All 39
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 15
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:198500 Nakahara M, et al., Gene-trap mutagenesis using Mol/MSM-1 embryonic stem cells from MSM/Ms mice. Mamm Genome. 2013 Jun;24(5-6):228-39

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory