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Sh3bp4 Gene Detail
Summary
  • Symbol
    Sh3bp4
  • Name
    SH3-domain binding protein 4
  • Synonyms
    BOG25
  • Feature Type
    protein coding gene
  • IDs
    MGI:2138297
    NCBI Gene: 98402
  • Gene Overview
    MyGene.info: SH3BP4
Location & Maps
more
  • Sequence Map
    Chr1:89070415-89155068 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      84654 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 45.05 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    SH3BP4, SH3 domain binding protein 4
  • Vertebrate Orthologs
    11
  • Human Ortholog
    SH3BP4, SH3 domain binding protein 4
    Orthology source: HomoloGene
  • Synonyms
    BOG25, TTP
  • Links
    NCBI Gene ID: 23677
    neXtProt AC: NX_Q9P0V3

  • Chr Location
    2q37.1-q37.2; chr2:234951984-235055714 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 8726
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;2 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: SH3BP4
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    15 phenotype references
  • All Mutations and Alleles
    148
  • Chemically induced (other)
    1
  • Gene trapped
    144
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Sh3bp4
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000029359 VEGA Gene Model | MGI Sequence Detail 84654 C57BL/6J ±  kb
transcript OTTMUST00000072746 VEGA | MGI Sequence Detail 4995 Not Applicable  
polypeptide OTTMUSP00000037525 VEGA | MGI Sequence Detail 962 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    676 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 5
Other
Accession IDs
less
MGI:2138581
References
more
  • Summaries
    All 34
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 15
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
  • Latest
    J:198500 Nakahara M, et al., Gene-trap mutagenesis using Mol/MSM-1 embryonic stem cells from MSM/Ms mice. Mamm Genome. 2013 Jun;24(5-6):228-39

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory