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Chst10
Gene Detail
Symbol

Name
ID
Chst10
carbohydrate sulfotransferase 10
MGI:2138283
Synonyms
Hnk-1st, ST
Feature Type
protein coding gene
Genetic Map
Chromosome 1
17.24 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr1:38863867-38898161 bp, - strand
From VEGA annotation of GRCm38

  34295 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:21013  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Chst10

Human
homologs
Human Homolog   CHST10, carbohydrate sulfotransferase 10
NCBI Gene ID 9486
neXtProt AC  NX_O43529
Human Synonyms  HNK1ST, HNK-1ST
Human Chr (Location)  2q11.2; chr2:100391860-100417668 (-)  GRCh38.p2
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutation of this gene results in altered synaptic transmission and long term potentiation. Mutant animals exhibit impaired spatial learning and long term memory deficits. Mice homozygous for a different knock-out allele exhibit reduced male and female fertility.
 
Phenotype Images(1)
Interactions
Chst10 interacts with 181 markers (Mir7-1, Mir10b, Mir17, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (2 records)
Data Summary: Results (7)    Tissues (6)    Tissue x Stage Matrix (view)
Assay TypeResults
RT-PCR 7
cDNA source data(43)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(45) cDNA(43) Primer pair(2)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000049487 (Evidence)
Ensembl Gene ModelENSMUSG00000026080 (Evidence)
Entrez Gene98388 (Evidence)
UniGene260054
DFCITC1576446, TC1589875
DoTSDT.94384600, DT.91322595, DT.485267, DT.101364788
NIA Mouse Gene IndexU021260
EC2.8.2.-
Consensus CDS ProjectCCDS14901.1
International Mouse Knockout Project StatusChst10
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000049487 VEGA Gene Model | MGI Sequence Detail 34295 C57BL/6J ±  kb
transcript OTTMUST00000127686 VEGA | MGI Sequence Detail 2975 Not Applicable 
polypeptide OTTMUSP00000068843 VEGA | MGI Sequence Detail 374 Not Applicable 

For the selected sequences
All sequences(69) RefSeq(6) UniProt(7)
Polymorphisms
SNPs within 2kb(454 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR018011 Carbohydrate sulfotransferase-related
InterPro IPR005331 Sulfotransferase
Protein Ontology PR:000005470 carbohydrate sulfotransferase 10
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:195651 Suzuki-Anekoji M, et al., In vivo regulation of steroid hormones by the Chst10 sulfotransferase in mouse. J Biol Chem. 2013 Feb 15;288(7):5007-16
All references(39)
Other
accession IDs
MGI:2138490

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/12/2015
MGI 5.21
The Jackson Laboratory