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Gorab Gene Detail
Summary
  • Symbol
    Gorab
  • Name
    golgin, RAB6-interacting
  • Synonyms
    NTKL-BP1, Scyl1bp1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2138271
    NCBI Gene: 98376
Location & Maps
more
  • Sequence Map
    Chr1:163384908-163403669 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      18762 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    GORAB, golgin, RAB6-interacting
  • Vertebrate Orthologs
    10
  • Human Ortholog
    GORAB, golgin, RAB6-interacting
    Orthology source: HGNC, HomoloGene
  • Synonyms
    GO, NTKLBP1, SCYL1BP1
  • Links
    NCBI Gene ID: 92344
    neXtProt AC: NX_Q5T7V8

  • Chr Location
    1q24.2; chr1:170532122-170553834 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 45113
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: GORAB
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with human GORAB associations

Human Disease Mouse Models
       Geroderma Osteodysplasticum; GO   OMIM: 231070
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    2
  • Gene trapped
    2
  • Genomic Mutations
    2 involving Gorab
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000049704 VEGA Gene Model | MGI Sequence Detail 18762 C57BL/6J ±  kb
transcript OTTMUST00000126603 VEGA | MGI Sequence Detail 2538 Not Applicable  
polypeptide OTTMUSP00000068439 VEGA | MGI Sequence Detail 368 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    204 from dbSNP Build 137
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000008148 RAB6-interacting golgin
  • InterPro Domains
    IPR007033 RAB6-interacting golgin
Molecular
Reagents
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  • All nucleic 30
    cDNA 30

    Microarray probesets 3
References
more
  • Summaries
    All 27
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 4
  • Earliest
    J:91812 Stryke D, et al., BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Nucleic Acids Res. 2003 Jan 1;31(1):278-81
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory