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Hmgn3
Gene Detail
Symbol

Name
ID
Hmgn3
high mobility group nucleosomal binding domain 3
MGI:2138069
Synonyms
1110002A15Rik, 6330514M13Rik, HMGN3a, HMGN3b, TRIP7
Feature Type
protein coding gene
Genetic Map
Chromosome 9
45.29 cM, cytoband E3.1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr9:83109948-83146685 bp, - strand
From VEGA annotation of GRCm38

  36738 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
Protein SuperFamily: nonhistone chromosomal protein HMG-17
Gene Tree: Hmgn3
Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Targeted(6)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null allele exhibit impaired glucose tolerance with decreased insulin serum levels and increased glucose serum levels during feeding.
 
Interactions
Hmgn3 interacts with 24 markers (Mir29a, Mir29b-1, Mir29b-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process chromatin modification, positive regulation of sequence-specific DNA binding transcription factor activity, ...
Component chromatin, nucleus
Function chromatin binding, DNA binding, ...
External Resources: FuncBase
Expression
Literature Summary: (9 records)
Data Summary: Results (75)    Tissues (62)    Images (32)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 19
RNA in situ 46
RT-PCR 10
cDNA source data(23)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(24) cDNA(23) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000034786 (Evidence)
Ensembl Gene ModelENSMUSG00000066456 (Evidence)
Entrez Gene94353 (Evidence)
DFCITC1588019, TC1619608, TC1585716, TC1578186
DoTSDT.101705354, DT.101371117, DT.101371118, DT.532489, DT.94121525, DT.99855161
Consensus CDS ProjectCCDS52872.1, CCDS52873.1
International Mouse Knockout Project StatusHmgn3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000034786 VEGA Gene Model | MGI Sequence Detail 36738 C57BL/6J ±  kb
transcript OTTMUST00000088419 VEGA | MGI Sequence Detail 855 Not Applicable 
polypeptide OTTMUSP00000065951 VEGA | MGI Sequence Detail 128 Not Applicable 

For the selected sequences
All sequences(80) RefSeq(8) UniProt(2)
Polymorphisms
SNPs within 2kb(299 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000079 High mobility group nucleosome-binding domain-containing family
Protein Ontology PR:000029547 high mobility group nucleosome-binding domain-containing protein 3
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:214095 Osipovich AB, et al., Insm1 promotes endocrine cell differentiation by modulating the expression of a network of genes that includes Neurog3 and Ripply3. Development. 2014 Aug;141(15):2939-49
All references(43)
Other
accession IDs
MGI:1914636, MGI:1923404, MGI:2143355

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory