About   Help   FAQ
Loxl2 Gene Detail
Summary
  • Symbol
    Loxl2
  • Name
    lysyl oxidase-like 2
  • Synonyms
    1110004B06Rik, 9430067E15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2137913
    NCBI Gene: 94352
Location & Maps
more
  • Sequence Map
    Chr14:69609068-69695834 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      86767 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    LOXL2, lysyl oxidase like 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    LOXL2, lysyl oxidase like 2
    Orthology source: HomoloGene
  • Synonyms
    LOR2, WS9-14
  • Links
    NCBI Gene ID: 4017
    neXtProt AC: NX_Q9Y4K0

  • Chr Location
    8p21.3; chr8:23296897-23404209 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Gene trapped
    1
  • Targeted
    4
  • Genomic Mutations
    1 involving Loxl2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000044487 VEGA Gene Model | MGI Sequence Detail 86767 C57BL/6J ±  kb
transcript OTTMUST00000117113 VEGA | MGI Sequence Detail 5316 Not Applicable  
polypeptide OTTMUSP00000065502 VEGA | MGI Sequence Detail 776 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    794 from dbSNP Build 137
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 10
    Primer pair 1

    Microarray probesets 2
Other
Accession IDs
less
MGI:1915706, MGI:2443992
References
more
  • Summaries
    All 32
    Developmental Gene Expression 4
    Gene Ontology 6
    Phenotypes 7
  • Earliest
    J:52798 Jang W, et al., Comparative sequence of human and mouse BAC clones from the mnd2 region of chromosome 2p13. Genome Res. 1999 Jan;9(1):53-61
  • Latest
    J:214961 Milgrom-Hoffman M, et al., Endothelial cells regulate neural crest and second heart field morphogenesis. Biol Open. 2014;3(8):679-88

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
02/02/2016
MGI 6.02
The Jackson Laboratory