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Loxl2
Gene Detail
Symbol

Name
ID
Loxl2
lysyl oxidase-like 2
MGI:2137913
Synonyms
1110004B06Rik, 9430067E15Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 14
36.06 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr14:69609068-69695834 bp, + strand
From VEGA annotation of GRCm38

  86767 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1742  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: LOXL2
Gene Tree: Loxl2

Human
homologs
LOXL2, lysyl oxidase-like 2
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 4017
neXtProt AC: NX_Q9Y4K0

Human Synonyms: LOR2, WS9-14

Human Chr (Location): 8p21.3; chr8:23296897-23404209 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(1) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Loxl2 interacts with 267 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (34 annotations)
Process cellular protein modification process, chromatin modification, ...
Component basement membrane, chromosome, ...
Function chromatin binding, copper ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (5)    Tissues (5)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 5
cDNA source data(9)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase loxl2 ; ZFIN loxl2a, loxl2b    NEW 
Molecular
reagents
All nucleic(11) cDNA(10) Primer pair(1)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000044487 (Evidence)
Ensembl Gene Model ENSMUSG00000034205 (Evidence)
Entrez Gene 94352 (Evidence)
DFCI TC1577580, TC1595279, TC1651892
DoTS DT.101380831, DT.103561603, DT.110753992, DT.50316176, DT.94207934
NIA Mouse Gene Index U015808
EC 1.4.3.13
Consensus CDS Project CCDS27241.1
International Mouse Phenotyping Consortium Status Loxl2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000044487 VEGA Gene Model | MGI Sequence Detail 86767 C57BL/6J ±  kb
transcript OTTMUST00000117114 VEGA | MGI Sequence Detail 3042 Not Applicable 
polypeptide OTTMUSP00000065503 VEGA | MGI Sequence Detail 776 Not Applicable 

For the selected sequences
All sequences(41) RefSeq(10) UniProt(2)
Polymorphisms
SNPs within 2kb(793 from dbSNP Build 137)    SNPs within 2kb including multiple locations(2265)
Protein-related
information
ResourceIDDescription
InterPro IPR001695 Lysyl oxidase
InterPro IPR019828 Lysyl oxidase, conserved site
InterPro IPR001190 Speract/scavenger receptor
InterPro IPR017448 Speract/scavenger receptor-related
Protein Ontology PR:000009885 lysyl oxidase homolog 2
References
(Earliest) J:52798 Jang W, et al., Comparative sequence of human and mouse BAC clones from the mnd2 region of chromosome 2p13. Genome Res. 1999 Jan;9(1):53-61
(Latest) J:214961 Milgrom-Hoffman M, et al., Endothelial cells regulate neural crest and second heart field morphogenesis. Biol Open. 2014;3(8):679-88
All references(35)
Other
accession IDs
MGI:1915706, MGI:2443992

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory