About   Help   FAQ
Loxl2
Gene Detail
Symbol

Name
ID
Loxl2
lysyl oxidase-like 2
MGI:2137913
BioType Conflict
Synonyms
1110004B06Rik, 9430067E15Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 14
36.06 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr14:69609068-69695834 bp, + strand
From VEGA annotation of GRCm38

  86767 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1742  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Human
homologs
Human Homolog LOXL2, lysyl oxidase-like 2
NCBI Gene ID 4017
neXtProt AC  NX_Q9Y4K0
Human Synonyms  LOR2, WS9-14
Human Chr (Location)  8p21.3; chr8:23296897-23404209 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(1) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Loxl2 interacts with 267 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (19 annotations)
Process cellular protein modification process, collagen fibril organization, ...
Component basement membrane, extracellular space, ...
Function chromatin binding, methylated histone binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (5)    Tissues (5)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 5
cDNA source data(9)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(11) cDNA(10) Primer pair(1)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000044487 (Evidence)
Ensembl Gene ModelENSMUSG00000034205 (Evidence), ENSMUSG00000098872 (Evidence)
Entrez Gene94352 (Evidence)
DFCITC1577580, TC1595279, TC1651892
DoTSDT.101380831, DT.103561603, DT.110753992, DT.50316176, DT.94207934
NIA Mouse Gene IndexU015808
Consensus CDS ProjectCCDS27241.1
International Mouse Knockout Project StatusLoxl2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000044487 VEGA Gene Model | MGI Sequence Detail 86767 C57BL/6J ±  kb
transcript OTTMUST00000117113 VEGA | MGI Sequence Detail 5316 Not Applicable 
polypeptide OTTMUSP00000065502 VEGA | MGI Sequence Detail 776 Not Applicable 

For the selected sequences
All sequences(41) RefSeq(10)
Polymorphisms
SNPs within 2kb(793 from dbSNP Build 137)    SNPs within 2kb including multiple locations(2265)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000009885 lysyl oxidase homolog 2
References
(Earliest) J:52798 Jang W, et al., Comparative sequence of human and mouse BAC clones from the mnd2 region of chromosome 2p13. Genome Res. 1999 Jan;9(1):53-61
(Latest) J:184120 Iftikhar M, et al., Lysyl oxidase-like-2 (LOXL2) is a major isoform in chondrocytes and is critically required for differentiation. J Biol Chem. 2011 Jan 14;286(2):909-18
All references(31)
Other
accession IDs
MGI:1915706, MGI:2443992

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/08/2014
MGI 5.20
The Jackson Laboratory