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Prcc Gene Detail
Summary
  • Symbol
    Prcc
  • Name
    papillary renal cell carcinoma (translocation-associated)
  • Feature Type
    protein coding gene
  • IDs
    MGI:2137738
    NCBI Gene: 94315
  • Gene Overview
    MyGene.info: PRCC
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:87858903-87885562 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 38.78 cM, cytoband F2.1-2.2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    75 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2137738
protein coding gene Chr3:87858903-87885608 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027371
protein coding gene Chr3:87985610-88014064 (-)
A/J MGP_AJ_G0027335
protein coding gene Chr3:84999025-85025179 (-)
AKR/J MGP_AKRJ_G0027301
protein coding gene Chr3:87079891-87109203 (-)
BALB/cJ MGP_BALBcJ_G0027344
protein coding gene Chr3:85096387-85124235 (-)
C3H/HeJ MGP_C3HHeJ_G0027087
protein coding gene Chr3:87351879-87379011 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027790
protein coding gene Chr3:91219552-91250777 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025143
protein coding gene Chr3:80623858-80650113 (-)
CAST/EiJ MGP_CASTEiJ_G0026534
protein coding gene Chr3:87567972-87600373 (-)
CBA/J MGP_CBAJ_G0027062
protein coding gene Chr3:94300338-94335036 (-)
DBA/2J MGP_DBA2J_G0027198
protein coding gene Chr3:84492607-84520641 (-)
FVB/NJ MGP_FVBNJ_G0027167
protein coding gene Chr3:82764019-82791670 (-)
LP/J MGP_LPJ_G0027306
protein coding gene Chr3:88946454-88973254 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027186
protein coding gene Chr3:100564022-100593685 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027848
protein coding gene Chr3:86836089-86863037 (-)
PWK/PhJ MGP_PWKPhJ_G0026267
protein coding gene Chr3:84287248-84315233 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026084
protein coding gene Chr3:86025836-86055102 (-)
WSB/EiJ MGP_WSBEiJ_G0026613
protein coding gene Chr3:87196724-87230651 (-)



Homology
more
  • Human Ortholog
    PRCC, proline rich mitotic checkpoint control factor
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PRCC, proline rich mitotic checkpoint control factor
    Orthology source: HGNC, HomoloGene
  • Synonyms
    RCCP1, TPRC
  • Links
    NCBI Gene ID: 5546
    neXtProt AC: NX_Q92733
    UniProt: Q92733

  • Chr Location
    1q23.1; chr1:156767482-156800819 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 38120
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: PRCC
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with human PRCC associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
  • All Mutations and Alleles
    37
  • Chemically induced (other)
    1
  • Gene trapped
    33
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Prcc
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 94315 NCBI Gene Model | MGI Sequence Detail 26660 C57BL/6J ±  kb
transcript NM_033573 RefSeq | MGI Sequence Detail 2090 C57BL/6  
polypeptide NP_291051 RefSeq | MGI Sequence Detail 491 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR018800 Proline-rich protein PRCC
Molecular
Reagents
less
  • All nucleic 25
    Genomic 1
    cDNA 24

    Microarray probesets 4
References
more
  • Summaries
    All 26
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 1
    Phenotypes 11
  • Earliest
    J:70457 Weterman MA, et al., Genomic structure, chromosomal localization, and embryonic expression of the mouse homolog of PRCC, a gene associated with papillary renal cell carcinoma. Cytogenet Cell Genet. 2001;92(3-4):326-32
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory