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Prcc Gene Detail
Summary
  • Symbol
    Prcc
  • Name
    papillary renal cell carcinoma (translocation-associated)
  • Feature Type
    protein coding gene
  • IDs
    MGI:2137738
    NCBI Gene: 94315
  • Gene Overview
    MyGene.info: PRCC
Location & Maps
more
  • Sequence Map
    Chr3:87858903-87885608 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      26706 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 38.78 cM, cytoband F2.1-2.2
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    PRCC, papillary renal cell carcinoma (translocation-associated)
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PRCC, papillary renal cell carcinoma (translocation-associated)
    Orthology source: HGNC, HomoloGene
  • Synonyms
    RCCP1, TPRC
  • Links
    NCBI Gene ID: 5546
    neXtProt AC: NX_Q92733

  • Chr Location
    1q21.1; chr1:156767482-156800817 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 38120
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: PRCC
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with human PRCC associations

Human Disease Mouse Models
       Renal Cell Carcinoma, Papillary, 1; RCCP1   OMIM: 605074
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    11 phenotype references
  • All Mutations and Alleles
    37
  • Chemically induced (other)
    1
  • Gene trapped
    33
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Prcc
  • Incidental Mutations
    APF
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000030643 VEGA Gene Model | MGI Sequence Detail 26706 C57BL/6J ±  kb
transcript OTTMUST00000075865 VEGA | MGI Sequence Detail 2099 Not Applicable  
polypeptide OTTMUSP00000039842 VEGA | MGI Sequence Detail 491 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    75 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR018800 Proline-rich protein PRCC
Molecular
Reagents
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  • All nucleic 25
    Genomic 1
    cDNA 24

    Microarray probesets 4
References
more
  • Summaries
    All 23
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 11
  • Earliest
    J:70457 Weterman MA, et al., Genomic structure, chromosomal localization, and embryonic expression of the mouse homolog of PRCC, a gene associated with papillary renal cell carcinoma. Cytogenet Cell Genet. 2001;92(3-4):326-32
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory