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Sfxn4 Gene Detail
Summary
  • Symbol
    Sfxn4
  • Name
    sideroflexin 4
  • Feature Type
    protein coding gene
  • IDs
    MGI:2137680
    NCBI Gene: 94281
Location & Maps
more
  • Sequence Map
    Chr19:60837277-60861479 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      24203 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 56.52 cM, cytoband D3
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    SFXN4, sideroflexin 4
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SFXN4, sideroflexin 4
    Orthology source: HGNC, HomoloGene
  • Synonyms
    BCRM1, COXPD18
  • Links
    NCBI Gene ID: 119559
    neXtProt AC: NX_Q6P4A7

  • Chr Location
    10q26.11; chr10:119140913-119165709 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 14228
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: SFXN4
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with human SFXN4 associations

Human Disease Mouse Models
       Combined Oxidative Phosphorylation Deficiency 18; COXPD18   OMIM: 615578
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021213 VEGA Gene Model | MGI Sequence Detail 24203 C57BL/6J ±  kb
transcript OTTMUST00000050248 VEGA | MGI Sequence Detail 1309 Not Applicable  
polypeptide OTTMUSP00000023436 VEGA | MGI Sequence Detail 313 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    419 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 14
    cDNA 14

    Microarray probesets 3
References
more
  • Summaries
    All 27
    Gene Ontology 6
    Phenotypes 4
  • Earliest
    J:68377 Fleming MD, et al., A mutation in a mitochondrial transmembrane protein is responsible for the pleiotropic hematological and skeletal phenotype of flexed-tail (f/f) mice. Genes Dev. 2001 Mar 15;15(6):652-7
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/23/2016
MGI 6.05
The Jackson Laboratory