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Sfxn4 Gene Detail
Summary
  • Symbol
    Sfxn4
  • Name
    sideroflexin 4
  • Feature Type
    protein coding gene
  • IDs
    MGI:2137680
    NCBI Gene: 94281
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:60837277-60861479 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 56.52 cM, cytoband D3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    419 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2137680
protein coding gene Chr19:60837270-60861700 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025297
protein coding gene Chr19:61447356-61473115 (-)
A/J MGP_AJ_G0025273
protein coding gene Chr19:58442891-58467791 (-)
AKR/J MGP_AKRJ_G0025242
protein coding gene Chr19:60267619-60296579 (-)
BALB/cJ MGP_BALBcJ_G0025268
protein coding gene Chr19:58526616-58552562 (-)
C3H/HeJ MGP_C3HHeJ_G0025028
protein coding gene Chr19:60512767-60539045 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025711
protein coding gene Chr19:62900842-62928193 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023123
protein coding gene Chr19:57270122-57293551 (-)
CAST/EiJ MGP_CASTEiJ_G0024493
protein coding gene Chr19:60615249-60641122 (-)
CBA/J MGP_CBAJ_G0025008
protein coding gene Chr19:65963455-65992383 (-)
DBA/2J MGP_DBA2J_G0025140
protein coding gene Chr19:58230389-58256446 (-)
FVB/NJ MGP_FVBNJ_G0025101
protein coding gene Chr19:57894984-57920426 (-)
LP/J MGP_LPJ_G0025226
protein coding gene Chr19:61276713-61304656 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025134
protein coding gene Chr19:65153774-65184713 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025769
protein coding gene Chr19:60509157-60534814 (-)
PWK/PhJ MGP_PWKPhJ_G0024241
protein coding gene Chr19:58170532-58195261 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024044
protein coding gene Chr19:59157744-59188485 (-)
WSB/EiJ MGP_WSBEiJ_G0024563
protein coding gene Chr19:60618130-60643342 (-)



Homology
more
  • Human Ortholog
    SFXN4, sideroflexin 4
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SFXN4, sideroflexin 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BCRM1, COXPD18, SLC56A4
  • Links
    NCBI Gene ID: 119559
    neXtProt AC: NX_Q6P4A7
    UniProt: Q6P4A7

  • Chr Location
    10q26.11; chr10:119140913-119165711 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 14228
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: SFXN4
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with human SFXN4 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000063698 Ensembl Gene Model | MGI Sequence Detail 24203 C57BL/6J ±  kb
transcript ENSMUST00000135808 Ensembl | MGI Sequence Detail 1309 Not Applicable  
polypeptide ENSMUSP00000118743 Ensembl | MGI Sequence Detail 313 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    cDNA 15

    Microarray probesets 3
References
more
  • Summaries
    All 28
    Gene Ontology 6
    Phenotypes 5
  • Earliest
    J:68377 Fleming MD, et al., A mutation in a mitochondrial transmembrane protein is responsible for the pleiotropic hematological and skeletal phenotype of flexed-tail (f/f) mice. Genes Dev. 2001 Mar 15;15(6):652-7
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory