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Sfxn3 Gene Detail
Summary
  • Symbol
    Sfxn3
  • Name
    sideroflexin 3
  • Feature Type
    protein coding gene
  • IDs
    MGI:2137679
    NCBI Gene: 94280
Location & Maps
more
  • Sequence Map
    Chr19:45047576-45056383 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      8808 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 38.26 cM, cytoband D1
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    SFXN3, sideroflexin 3
  • Vertebrate Orthologs
    9
  • Human Ortholog
    SFXN3, sideroflexin 3
    Orthology source: HGNC, HomoloGene
  • Synonyms
    BA108L7.2, SFX3
  • Links
    NCBI Gene ID: 81855
    neXtProt AC: NX_Q9BWM7

  • Chr Location
    10q24.31; chr10:101031229-101041241 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    4
  • Targeted
    4
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000025212 Ensembl Gene Model | MGI Sequence Detail 8808 C57BL/6J ±  kb
transcript ENSMUST00000062213 Ensembl | MGI Sequence Detail 2966 Not Applicable  
polypeptide ENSMUSP00000059419 Ensembl | MGI Sequence Detail 321 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    93 from dbSNP Build 142
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000014778 sideroflexin-3
  • InterPro Domains
    IPR004686 Tricarboxylate/iron carrier
Molecular
Reagents
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  • All nucleic 77
    cDNA 77

    Microarray probesets 3
References
more
  • Summaries
    All 27
    Gene Ontology 6
    Phenotypes 4
  • Earliest
    J:68377 Fleming MD, et al., A mutation in a mitochondrial transmembrane protein is responsible for the pleiotropic hematological and skeletal phenotype of flexed-tail (f/f) mice. Genes Dev. 2001 Mar 15;15(6):652-7
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory