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Sfxn1 Gene Detail
Summary
  • Symbol
    Sfxn1
  • Name
    sideroflexin 1
  • Synonyms
    2810002O05Rik, A930015P12Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2137677
    NCBI Gene: 14057
  • Gene Overview
    MyGene.info: SFXN1
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:54071869-54108342 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 28.40 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    534 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2137677
protein coding gene Chr13:54071825-54108346 (.)
129S1/SvImJ MGP_129S1SvImJ_G0020565
protein coding gene Chr13:53446615-53485413 (+)
A/J MGP_AJ_G0020519
protein coding gene Chr13:51495233-51531698 (+)
AKR/J MGP_AKRJ_G0020497
protein coding gene Chr13:52999537-53042228 (+)
BALB/cJ MGP_BALBcJ_G0020515
protein coding gene Chr13:51717224-51754329 (+)
C3H/HeJ MGP_C3HHeJ_G0020314
protein coding gene Chr13:52822724-52864754 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020949
protein coding gene Chr13:55085076-55131758 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018531
protein coding gene Chr13:49501574-49538306 (+)
CAST/EiJ MGP_CASTEiJ_G0019828
protein coding gene Chr13:52886354-52924521 (+)
CBA/J MGP_CBAJ_G0020274
protein coding gene Chr13:57164985-57206504 (+)
DBA/2J MGP_DBA2J_G0020397
protein coding gene Chr13:51068610-51105274 (+)
FVB/NJ MGP_FVBNJ_G0020376
protein coding gene Chr13:50515399-50554538 (+)
LP/J MGP_LPJ_G0020473
protein coding gene Chr13:53718968-53756733 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020405
protein coding gene Chr13:56688836-56728370 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020992
protein coding gene Chr13:52601446-52640106 (+)
PWK/PhJ MGP_PWKPhJ_G0019584
protein coding gene Chr13:51024813-51061693 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019411
protein coding gene Chr13:51501690-51538996 (+)
WSB/EiJ MGP_WSBEiJ_G0019890
protein coding gene Chr13:52929210-52967673 (+)



Homology
more
  • Human Ortholog
    SFXN1, sideroflexin 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SFXN1, sideroflexin 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    SLC56A1, TCC
  • Links
    NCBI Gene ID: 94081
    neXtProt AC: NX_Q9H9B4
    UniProt: Q9H9B4

  • Chr Location
    5q35.2; chr5:175478498-175529742 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    19 phenotype references
  • All Mutations and Alleles
    24
  • Chemically induced (other)
    1
  • Gene trapped
    15
  • Spontaneous
    1
  • Targeted
    6
  • Transgenic
    1
  • Genomic Mutations
    1 involving Sfxn1
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021474 Ensembl Gene Model | MGI Sequence Detail 36474 C57BL/6J ±  kb
transcript ENSMUST00000021930 Ensembl | MGI Sequence Detail 2783 Not Applicable  
polypeptide ENSMUSP00000021930 Ensembl | MGI Sequence Detail 322 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 140
    cDNA 140

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-9693, MGI:1917369, MGI:2443662
References
more
  • Summaries
    All 67
    Developmental Gene Expression 2
    Gene Ontology 7
    Phenotypes 19
  • Earliest
    J:12951 Hunt HR, et al., Flexed Tail in the Mouse, Mus Musculus. Genetics. 1933 Jul;18(4):335-66
  • Latest
    J:198500 Nakahara M, et al., Gene-trap mutagenesis using Mol/MSM-1 embryonic stem cells from MSM/Ms mice. Mamm Genome. 2013 Jun;24(5-6):228-39

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory