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Snx18
Gene Detail
Symbol

Name
ID
Snx18
sorting nexin 18
MGI:2137642
Synonyms
Snag1
Feature Type
protein coding gene
Genetic Map
Chromosome 13
64.00 cM, cytoband D2.2
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr13:113592180-113618564 bp, - strand
From Ensembl annotation of GRCm38

  26385 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:14164  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: SNX18
Protein SuperFamily: sorting nexin, Snx9 type
Gene Tree: Snx18

Human
homologs
SNX18, sorting nexin 18
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 112574
neXtProt AC: NX_Q96RF0

Human Synonyms: SH3PX2, SH3PXD3B, SNAG1

Human Chr (Location): 5q11.2; chr5:54517759-54546586 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(46) : Gene trapped(44) Targeted(2)
Incidental mutations (data from APF )
Interactions
Snx18 interacts with 349 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (30 annotations)
Process cell cycle, cell division, ...
Component clathrin-coated vesicle, cytoplasmic membrane-bounded vesicle, ...
Function lipid binding, phosphatidylinositol-4,5-bisphosphate binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (38)    Tissues (11)    Images (17)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 38
cDNA source data(40)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase snx18    NEW 
Molecular
reagents
All nucleic(41) cDNA(41)
Microarray probesets(5)
Other database
links
Ensembl Gene Model ENSMUSG00000042364 (Evidence)
Entrez Gene 170625 (Evidence)
UniGene 33721
DFCI TC1575200
DoTS DT.101121310, DT.526988, DT.101376987
NIA Mouse Gene Index U035191
Consensus CDS Project CCDS36784.1
International Mouse Phenotyping Consortium Status Snx18
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000042364 Ensembl Gene Model | MGI Sequence Detail 26385 C57BL/6J ±  kb
transcript ENSMUST00000109241 Ensembl | MGI Sequence Detail 4446 Not Applicable 
polypeptide ENSMUSP00000104864 Ensembl | MGI Sequence Detail 615 Not Applicable 

For the selected sequences
All sequences(30) RefSeq(2) UniProt(4)
Polymorphisms
SNPs within 2kb(381 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001683 Phox homologous domain
InterPro IPR019497 Sorting nexin protein, WASP-binding domain
InterPro IPR014536 Sorting nexin, Snx9 type
InterPro IPR001452 Src homology-3 domain
Protein Ontology PR:000015367 sorting nexin-18
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:169751 Nakazawa S, et al., Expression of Sorting Nexin 18 (SNX18) Is Dynamically Regulated in Developing Spinal Motor Neurons. J Histochem Cytochem. 2011 Feb;59(2):202-13
All references(34)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/20/2015
MGI 5.22
The Jackson Laboratory